Y Chromosome Loss Drives Bladder Cancer Aggressiveness and Immune Evasion
- PMID: 37387586
- DOI: 10.1158/2159-8290.CD-RW2023-102
Y Chromosome Loss Drives Bladder Cancer Aggressiveness and Immune Evasion
Abstract
Loss of the Y chromosome contributes to the aggressiveness of bladder cancer through T-cell dysfunction.
©2023 American Association for Cancer Research.
Comment on
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Y chromosome loss in cancer drives growth by evasion of adaptive immunity.Nature. 2023 Jul;619(7970):624-631. doi: 10.1038/s41586-023-06234-x. Epub 2023 Jun 21. Nature. 2023. PMID: 37344596 Free PMC article.
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