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Case Reports
. 2023 Jun 27;2023(6):rjad360.
doi: 10.1093/jscr/rjad360. eCollection 2023 Jun.

Symptomatic acinar cell cystadenoma of the pancreas

William Sergi  1 , Stefano D'Ugo  1 , Annarita Libia  1 , Norma Depalma  1 , Tiziana Marchese  1 , Stefano Garritano  1 , Stefania Vadrucci  1 , Elisa Stasi  1   2 , Ivan Botrugno  1 , Farshad Manoochehri  1 , Marcello Spampinato  1 , William Sergi  1
Affiliations
Case Reports

Symptomatic acinar cell cystadenoma of the pancreas

William Sergi et al. J Surg Case Rep. .

Abstract

Acinar cystic transformation (ACT), also known as 'acinar cell cystadenoma', is an uncommon cystic neoplasm of pancreas with unknown malignant potential. This case regards a woman with symptomatic pancreatic head ACT, revealed with pathological exam of specimen after pancreaticoduodenectomy. A 57-years-old patient presented mild hyperbilirubinemia and recurrent cholangitis; she underwent to ERCP, EUS and MRI, and these exams revealed a large cyst of the pancreatic head that caused biliary compression. The discussion of the case by the multidisciplinary group indicated surgical resection. Pancreatic ACT is so rare, and its preoperative diagnosis is difficult. The symptoms of the patients and the features of the cyst are the criteria to choose a surgical resection.

Keywords: acinar cystic transformation - acinar cell cystadenoma - pancreatic cystic neoplasm - pancreaticoduodenectomy.

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Conflict of interest statement

None declared.

Figures

Figure 1
Figure 1
Radiological features of a large complex cyst of the pancreatic head.
Figure 2
Figure 2
Endoscopic features of an IPMN-like lesion.
Figure 3
Figure 3
Multiple cists of variable sizes containing amorphous material (A, H&E ×10) and connected to acini (B, H&E ×10); Islet of Langerhans with microcystic dilation (C, H&E ×20); positive immunohistochemical stain for trypsin (D).
See this image and copyright information in PMC

References

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