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. 2023 Apr 18:10:1120487.
doi: 10.3389/fcvm.2023.1120487. eCollection 2023.

Falling corin and ANP activity levels accelerate development of heart failure and cardiac fibrosis

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Falling corin and ANP activity levels accelerate development of heart failure and cardiac fibrosis

Inna P Gladysheva et al. Front Cardiovasc Med. .
No abstract available

Keywords: atrial natriuretic peptide; corin; dilated cardiomyopathy; edema; fibrosis.

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Conflict of interest statement

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Figures

Figure 1
Figure 1
Schematic representation of the pathological shift of the cardiac corin-atrial natriuretic peptide (ANP) axis and classical RAAS [renin-angiotensin II (Ang II)—aldosterone] axis in dilated cardiomyopathy, which promotes cardiac fibrosis, edema and accelerates HFrEF progression.

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