Medical imaging in the assessment of cardiovascular disease risk
- PMID: 37389461
- DOI: 10.1097/MCO.0000000000000960
Medical imaging in the assessment of cardiovascular disease risk
Abstract
Purpose of review: The prevalence of obesity has exponentially increased during the past years. The assessment of human adipose tissue distribution enables the identification of diverse ectopic adipose tissue depots, and helps to explain its relationship with cardiovascular health status. In this review, we summarize the current methods used in the assessment of human adipose tissue distribution, and we discuss the relationship between ectopic adipose tissue distribution and the risk of developing cardiovascular diseases and metabolic complications.
Recent findings: The reference instruments to assess human adipose tissue distribution nowadays are the computed tomography and the magnetic resonance imaging (MRI). Today, MRI is the preferred imaging technique and enables the measurement of variations in the distribution of body adipose tissue among different phenotypes and individuals. This technique has helped to better understand the relationship between different ectopic adipose tissue depots and its relationship with cardiometabolic health among individuals.
Summary: Although body composition can be assessed by simple techniques, these calculations can provide erroneous results and conclusions, requiring complex interpretations when diverse metabolic situations are concomitantly engaged. Contrarily, medical imaging techniques (e.g. MRI) enables to objectively and unbiasedly measure changes that may occur during longitudinal studies (e.g. pharmacological drug interventions).
Copyright © 2023 Wolters Kluwer Health, Inc. All rights reserved.
References
-
- Valenzuela PL, Carrera-Bastos P, Castillo-García A, et al. Obesity and the risk of cardiometabolic diseases. Nat Rev Cardiol 2023; 20:475–494.
-
- Neeland IJ, Ross R, Després JP, et al. Visceral and ectopic fat, atherosclerosis, and cardiometabolic disease: a position statement. Lancet Diabetes Endocrinol 2019; 7:715–725.
-
- Chartrand DJ, Murphy-Després A, Alméras N, et al. Overweight, obesity, and CVD risk: a focus on visceral/ectopic fat. Curr Atheroscler Rep 2022; 24:185–195.
-
- Sattar N, McMurray JJV, McInnes IB, et al. Treating chronic diseases without tackling excess adiposity promotes multimorbidity. Lancet Diabetes Endocrinol 2023; 11:58–62.
-
- Elsayed NA, Aleppo G, Aroda VR, et al. on behalf of the American Diabetes Association. 8. Obesity and weight management for the prevention and treatment of type 2 diabetes: standards of care in diabetes-2023. Diabetes Care 2023; 46: (Suppl 1): S128–S139.
Publication types
MeSH terms
LinkOut - more resources
Full Text Sources
Research Materials
Miscellaneous
