Cardiotoxic effects of antitumor agents
- PMID: 373905
- DOI: 10.1007/BF00253143
Cardiotoxic effects of antitumor agents
Abstract
Cardiotoxic effects related to treatment with some antitumor agents (chiefly anthracycline antibiotics, cylophosphamide, corticosteroids, 5-fluorouracil, and radiation therapy), their association, and contemporaneous administration of other (potentially) cardiotoxic drugs are reviewed. Experimental models, clinical findings, and diagnostic methods are briefly described. Pathogenetic factors and interactions of antitumor drugs with biomembranes, DNA, and immune reactions are discussed.
Similar articles
-
Cardiotoxicity of chemotherapeutic agents: incidence, treatment and prevention.Drug Saf. 2000 Apr;22(4):263-302. doi: 10.2165/00002018-200022040-00002. Drug Saf. 2000. PMID: 10789823 Review.
-
Anthracycline cardiotoxicity in breast cancer patients: synergism with trastuzumab and taxanes.Cardiovasc Toxicol. 2007;7(2):67-71. doi: 10.1007/s12012-007-0013-5. Cardiovasc Toxicol. 2007. PMID: 17652806 Review.
-
[Chemotherapy and cardiotoxicity].Ann Cardiol Angeiol (Paris). 1995 Oct;44(8):443-7. Ann Cardiol Angeiol (Paris). 1995. PMID: 8669796 French.
-
Anthracycline-induced cardiotoxicity: course, pathophysiology, prevention and management.Expert Opin Pharmacother. 2007 Jun;8(8):1039-58. doi: 10.1517/14656566.8.8.1039. Expert Opin Pharmacother. 2007. PMID: 17516870 Review.
-
Cardiotoxicity of doxorubicin and other anthracycline derivatives.J Nucl Cardiol. 2000 Jan-Feb;7(1):53-62. doi: 10.1067/mnc.2000.103324. J Nucl Cardiol. 2000. PMID: 10698235 Review. No abstract available.
Cited by
-
The clinical syndrome of 5-fluorouracil cardiotoxicity.Invest New Drugs. 1989 Apr;7(1):101-9. doi: 10.1007/BF00178196. Invest New Drugs. 1989. PMID: 2737845
-
Acute negative inotropic effect of adriamycin (doxorubicin).Naunyn Schmiedebergs Arch Pharmacol. 1981 Nov;317(3):252-6. doi: 10.1007/BF00503826. Naunyn Schmiedebergs Arch Pharmacol. 1981. PMID: 7322214
-
Antitumor chemotherapy after fluorouracil angina.J Cancer Res Clin Oncol. 1982;104(3):321-2. doi: 10.1007/BF00406251. J Cancer Res Clin Oncol. 1982. PMID: 7161314 Free PMC article. No abstract available.