Potential conflicts of interest. S. A. reports payment or honoraria for lectures, presentations, speakers’ bureaus, manuscript writing, or educational events from Pfizer; and support for attending meetings and/or travel from Pfizer and MSD. C. G. reports payment or honoraria for lectures, presentations, speakers’ bureaus, manuscript writing. or educational events from Gilead, ViiV, MSD, and Jansen; and support for attending meetings and/or travel from Gilead, ViiV, MSD, and Jansen. A. G. reports consulting fees from Myland and Jansen; payment or honoraria for lectures, presentations, speakers’ bureaus, manuscript writing, or educational events from Gilead and ViiV; payment for expert testimony from Jansen; support for attending meetings and/or travel from Gilead, ViiV, and MSD. All other authors report no potential conflicts. All authors have submitted the ICMJE Form for Disclosure of Potential Conflicts of Interest. Conflicts that the editors consider relevant to the content of the manuscript have been disclosed.