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. 2023 Sep;8(3):1049-1053.
doi: 10.1002/epi4.12782. Epub 2023 Jul 11.

Clinical characteristics and follow-up of children with norovirus-associated benign convulsions with mild gastroenteritis

Kaili Shi  1 , Daoju Jiang  2 , Jiehui Yang  3 , Ying Li  1 , Wenxiong Chen  1 , Peiqing Li  2
Affiliations

Clinical characteristics and follow-up of children with norovirus-associated benign convulsions with mild gastroenteritis

Kaili Shi et al. Epilepsia Open. 2023 Sep.

Abstract

Objective: Explore the clinical characteristics and prognosis of children with norovirus (NoV)-associated benign convulsions with mild gastroenteritis (CwG).

Methods: We retrospectively analyzed the Clinical and laboratory data of children with NoV-associated CwG admitted to the emergency department of Guangzhou Children's Hospital between January 2019 and January 2020. And patients were followed up for 23-36 months.

Results: There are 49 cases met the CwG criteria. Vomiting was the first symptom in 31 (63.3%) patients, and vomiting could be the main or the only gastrointestinal symptom. The mean frequency of seizures was 3.8 ± 2.4 episodes. Most patients (95.9%) experienced seizures that lasted for less than 5 min. Of the 43 (87.8%) cases followed up from 23 to 36 months, only one experienced recurrent convulsions (after rotavirus infection).

Significance: NoV-associated CwG patients were prone to experiencing more convulsions. However, because most NoV-associated CwG patients had good prognosis, long-term use of anticonvulsants are unnecessary.

Keywords: children; clinical characteristics; convulsions; gastroenteritis; norovirus.

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Conflict of interest statement

The authors declare that there is no conflict of interest.

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