Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2023 Sep;8(3):1049-1053.
doi: 10.1002/epi4.12782. Epub 2023 Jul 11.

Clinical characteristics and follow-up of children with norovirus-associated benign convulsions with mild gastroenteritis

Kaili Shi  1 , Daoju Jiang  2 , Jiehui Yang  3 , Ying Li  1 , Wenxiong Chen  1 , Peiqing Li  2
Affiliations

Clinical characteristics and follow-up of children with norovirus-associated benign convulsions with mild gastroenteritis

Kaili Shi et al. Epilepsia Open. 2023 Sep.

Abstract

Objective: Explore the clinical characteristics and prognosis of children with norovirus (NoV)-associated benign convulsions with mild gastroenteritis (CwG).

Methods: We retrospectively analyzed the Clinical and laboratory data of children with NoV-associated CwG admitted to the emergency department of Guangzhou Children's Hospital between January 2019 and January 2020. And patients were followed up for 23-36 months.

Results: There are 49 cases met the CwG criteria. Vomiting was the first symptom in 31 (63.3%) patients, and vomiting could be the main or the only gastrointestinal symptom. The mean frequency of seizures was 3.8 ± 2.4 episodes. Most patients (95.9%) experienced seizures that lasted for less than 5 min. Of the 43 (87.8%) cases followed up from 23 to 36 months, only one experienced recurrent convulsions (after rotavirus infection).

Significance: NoV-associated CwG patients were prone to experiencing more convulsions. However, because most NoV-associated CwG patients had good prognosis, long-term use of anticonvulsants are unnecessary.

Keywords: children; clinical characteristics; convulsions; gastroenteritis; norovirus.

PubMed Disclaimer

Conflict of interest statement

The authors declare that there is no conflict of interest.

References

    1. Morooka K. Convulsions and mild diarrhea. Shonika. 1982;23:131–137.
    1. Bonkoungou I, Ouédraogo N, Tamini L, Teguera RK, Yaméogo P, Drabo MK, et al. Rotavirus and norovirus in children with severe diarrhea in Burkina Faso before rotavirus vaccine introduction. J Med Virol. 2018;90:1453–1460. - PubMed
    1. Payne DC, Vinjé J, Szilagyi PG, Edwards KM, Staat MA, Weinberg GA, et al. Norovirus and medically attended gastroenteritis in U.S. children. N Engl J Med. 2013;368:1121–1130. - PMC - PubMed
    1. Jin HI, Lee YM, Choi YJ, Jeong SJ. Recent viral pathogen in acute gastroenteritis: a retrospective study at a tertiary hospital for 1 year. Korean J Pediatr. 2016;59:120–125. - PMC - PubMed
    1. Abe T, Kobayashi M, Araki K, Kodama H, Fujita Y, Shinozaki T, et al. Infantile convulsions with mild gastroenteritis. Brain Dev. 2000;22:301–306. - PubMed