doi: 10.1007/BF00691434.
Enteric nerves in diabetic rats: electron microscopic evidence for neuropathy of vasoactive intestinal polypeptide-containing fibres
- PMID: 3739623
- DOI: 10.1007/BF00691434
Item in Clipboard
Enteric nerves in diabetic rats: electron microscopic evidence for neuropathy of vasoactive intestinal polypeptide-containing fibres
Acta Neuropathol.
1986.
Abstract
Enteric nerves in the ileum of rats 8 weeks after streptozotocin-induction of diabetes were examined under the electron microscope before and after immunolabeling for vasoactive intestinal polypeptide (VIP). These studies have provided evidence of degenerative changes in the myenteric nerve fibres of diabetic rats, many of which were shown to contain VIP. It is suggested that VIP-ergic nerves in the gut may play a role in the development of gastrointestinal dysfunction in diabetes.
Similar articles
-
Effect of aminoguanidine treatment on diabetes-induced changes in the myenteric plexus of rat ileum.Auton Neurosci. 2007 Mar 30;132(1-2):16-26. doi: 10.1016/j.autneu.2006.08.007. Epub 2006 Sep 20. Auton Neurosci. 2007. PMID: 16987713
-
Enteric nerves in diabetic rats: increase in vasoactive intestinal polypeptide but not substance P.Gastroenterology. 1985 Nov;89(5):967-76. doi: 10.1016/0016-5085(85)90195-7. Gastroenterology. 1985. PMID: 2412933
-
Prevention and partial reversal of diabetes-induced changes in enteric nerves of the rat ileum by combined treatment with alpha-lipoic acid and evening primrose oil.Auton Neurosci. 2004 Mar 31;111(1):57-65. doi: 10.1016/j.autneu.2004.02.004. Auton Neurosci. 2004. PMID: 15109939
-
Reversal of nerve damage in streptozotocin-diabetic rats by acute application of insulin in vitro.Clin Sci (Lond). 1988 Dec;75(6):629-35. doi: 10.1042/cs0750629. Clin Sci (Lond). 1988. PMID: 3061714
-
Vasoactive intestinal polypeptide (VIP) as a cholinergic co-transmitter: some recent results.Cell Biol Int Rep. 1989 Dec;13(12):1039-51. doi: 10.1016/0309-1651(89)90018-0. Cell Biol Int Rep. 1989. PMID: 2699832 Review.
Cited by
-
Effect of streptozotocin-induced diabetes mellitus on release of vasoactive intestinal polypeptide from rodent small intestine.Dig Dis Sci. 1995 Apr;40(4):828-36. doi: 10.1007/BF02064987. Dig Dis Sci. 1995. PMID: 7720477
-
Parkinson's disease: an immunohistochemical study of Lewy body-containing neurons in the enteric nervous system.Acta Neuropathol. 1990;79(6):581-3. doi: 10.1007/BF00294234. Acta Neuropathol. 1990. PMID: 1972853
-
Effect of vitamin E on diabetes-induced changes in small intestine and plasma antioxidant capacity in rat.J Physiol Biochem. 2006 Sep;62(3):171-7. doi: 10.1007/BF03168466. J Physiol Biochem. 2006. PMID: 17451158
-
Effects of vitamin E deficiency on autonomic neuroeffector mechanisms in the rat caecum, vas deferens and urinary bladder.J Physiol. 1995 Sep 15;487 ( Pt 3)(Pt 3):773-86. doi: 10.1113/jphysiol.1995.sp020917. J Physiol. 1995. PMID: 8544138 Free PMC article.
References
Publication types
MeSH terms
Substances
LinkOut - more resources
Medical