Wnt genes in colonic polyposis predisposition

Isabel Quintana¹, Mariona Terradas¹, Pilar Mur^{1

2}, Iris B A W Te Paske^{3

4}, Sophia Peters^{4

5

6}, Isabel Spier^{4

5

6}, Verena Steinke-Lange^{4

7

8}, Claudia Maestro¹, David Torrents^{9

10}, Montserrat Puiggròs⁹, Romina Royo⁹, Raul Tonda¹¹, Genís Parra¹¹, Davide Piscia¹¹, Sergi Beltrán^{11

12

13}, Matilde Navarro^{1

2}, Virginia Piñol¹⁴, Joan Brunet^{1

2

15}, Noemi Gonzalez-Abuin¹, Gemma Aiza¹, Anna Sommer^{4

5

6}, Yasmijn van Herwaarden^{4

16}, Galuh Astuti^{4

17}, Elke Holinski-Feder^{4

7

8}, Nicoline Hoogerbrugge^{3

4}, Richarda M de Voer^{3

4}, Stefan Aretz^{4

5

6}, Gabriel Capellá^{1

2

4}, Laura Valle^{1

2

4}

Affiliations

¹ Hereditary Cancer Program, Catalan Institute of Oncology; Oncobell Program, IDIBELL, Hospitalet de Llobregat, Barcelona 08908, Spain.
² Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), Madrid 28029, Spain.
³ Department of Human Genetics, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, GA Nijmegen 6525, the Netherlands.
⁴ Member of SOLVE-RD ERN-GENTURIS.
⁵ Institute of Human Genetics, Medical Faculty, University of Bonn, Bonn 53127, Germany.
⁶ National Center for Hereditary Tumor Syndromes, University Hospital Bonn, Bonn 53127, Germany.
⁷ Medizinische Klinik Und Poliklinik IV, Campus Innenstadt, Klinikum Der Universität München, Munich 80336, Germany.
⁸ MGZ - Medizinisch Genetisches Zentrum, Munich 80335, Germany.
⁹ Life Sciences Department, Barcelona Supercomputing Center (BSC), Barcelona 08034, Spain.
¹⁰ ICREA, Barcelona 08010, Spain.
¹¹ CNAG-CRG, Centre for Genomic Regulation (CRG), Barcelona Institute of Science and Technology, Barcelona 08028, Spain.
¹² Universitat Pompeu Fabra (UPF), Barcelona 08002, Spain.
¹³ Department of Genetics, Microbiology and Statistics, School of Biology, Universitat de Barcelona (UB), Barcelona 08028, Spain.
¹⁴ Gastroenterology Unit, Hospital Universitario de Girona Dr Josep Trueta, Girona 17007, Spain.
¹⁵ Catalan Institute of Oncology, IDIBGi, Girona 17007, Spain.
¹⁶ Department of Gastroenterology and Hepatology, Radboud University Medical Center, GA Nijmegen 6525, the Netherlands.
¹⁷ Department of Human Genetics, Radboud University Medical Center, GA Nijmegen 6525, the Netherlands.

PMID: 37396538
PMCID: PMC10308148
DOI: 10.1016/j.gendis.2022.12.002

Wnt genes in colonic polyposis predisposition

Isabel Quintana et al. Genes Dis. 2022.

. 2022 Dec 29;10(3):753-757.

doi: 10.1016/j.gendis.2022.12.002. eCollection 2023 May.

Authors

Affiliations

¹ Hereditary Cancer Program, Catalan Institute of Oncology; Oncobell Program, IDIBELL, Hospitalet de Llobregat, Barcelona 08908, Spain.
² Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), Madrid 28029, Spain.
³ Department of Human Genetics, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, GA Nijmegen 6525, the Netherlands.
⁴ Member of SOLVE-RD ERN-GENTURIS.
⁵ Institute of Human Genetics, Medical Faculty, University of Bonn, Bonn 53127, Germany.
⁶ National Center for Hereditary Tumor Syndromes, University Hospital Bonn, Bonn 53127, Germany.
⁷ Medizinische Klinik Und Poliklinik IV, Campus Innenstadt, Klinikum Der Universität München, Munich 80336, Germany.
⁸ MGZ - Medizinisch Genetisches Zentrum, Munich 80335, Germany.
⁹ Life Sciences Department, Barcelona Supercomputing Center (BSC), Barcelona 08034, Spain.
¹⁰ ICREA, Barcelona 08010, Spain.
¹¹ CNAG-CRG, Centre for Genomic Regulation (CRG), Barcelona Institute of Science and Technology, Barcelona 08028, Spain.
¹² Universitat Pompeu Fabra (UPF), Barcelona 08002, Spain.
¹³ Department of Genetics, Microbiology and Statistics, School of Biology, Universitat de Barcelona (UB), Barcelona 08028, Spain.
¹⁴ Gastroenterology Unit, Hospital Universitario de Girona Dr Josep Trueta, Girona 17007, Spain.
¹⁵ Catalan Institute of Oncology, IDIBGi, Girona 17007, Spain.
¹⁶ Department of Gastroenterology and Hepatology, Radboud University Medical Center, GA Nijmegen 6525, the Netherlands.
¹⁷ Department of Human Genetics, Radboud University Medical Center, GA Nijmegen 6525, the Netherlands.

PMID: 37396538
PMCID: PMC10308148
DOI: 10.1016/j.gendis.2022.12.002

No abstract available

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References

1. Muller C., Yamada A., Ikegami S., et al. Risk of colorectal cancer in serrated polyposis syndrome: a systematic review and meta-analysis. Clin Gastroenterol Hepatol. 2022;20(3):622–630. e7. - PubMed
1. Valle L., de Voer R.M., Goldberg Y., et al. Update on genetic predisposition to colorectal cancer and polyposis. Mol Aspect Med. 2019;69:10–26. - PubMed
1. Quintana I., Mejías-Luque R., Terradas M., et al. Evidence suggests that germline RNF43 mutations are a rare cause of serrated polyposis. Gut. 2018;67(12):2230–2232. - PubMed
1. Shang S., Hua F., Hu Z.W. The regulation of β-catenin activity and function in cancer: therapeutic opportunities. Oncotarget. 2017;8(20):33972–33989. - PMC - PubMed

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Wnt genes in colonic polyposis predisposition

Affiliations

Wnt genes in colonic polyposis predisposition

Authors

Affiliations

References

LinkOut - more resources

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