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. 2022 Sep 16;15(2):9569.
doi: 10.4081/dr.2022.9569. eCollection 2023 Jun 7.

A rare ossifying trichilemmal cyst in a young female patient: a case report and literature review

Evanthia Serpetsidaki  1 , Ioannis G Gkionis  2 , Roxani N Arvelaki  2 , Zafeiro I Karafoulidou  2 , Anastasios F Dimou  2 , Maria Kafousi  3
Affiliations

A rare ossifying trichilemmal cyst in a young female patient: a case report and literature review

Evanthia Serpetsidaki et al. Dermatol Reports. .

Abstract

Trichilemmal cysts (TCs) constitute the second most common cutaneous cysts and are mostly presented on the scalp of middleaged women. Therefore, it is unusual for a young person to have a TC and it is extremely rare for a TC to be ossified. In the literature, only 8 cases of TCs with concomitant ossification have been described. We report the case of a 22-year-old female who presented with a scalp nodule and was treated via surgical excision of the lesion. The pathology examination of the surgical specimen revealed a lesion consisting of a multilayered squamous epithelium of slightly eosinophilic maturing keratinocytes. There was no granular layer, whereas the core of the lesion was occupied by mature bone tissue with calcium deposits. The definite diagnosis of the pathology report was ossifying TC. The aim of this report is, to enlighten clinicians about this rare pathological entity.

Keywords: ossification; recurrence; surgical excision; trichilemmal cyst.

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Conflict of interest statement

Conflict of interest: the authors declare no potential conflict of interest.

Figures

Figure 1.
Figure 1.
Stratified squamous epithelium of the trichilemmal cyst with mature bone tissue within it (Hematoxylin and Eosin stain 2.5x). The image was processed with the use of MS Paint, edition 6.1, 2009 Microsoft Corporation.
Figure 2.
Figure 2.
Closer view of the mature bone tissue in the core of the trichilemmal cyst (Hematoxylin and Eosin stain 10x). The arrow is demonstrating the bone tissue with sub-cellular marrow. The image was processed with the use of MS Paint, edition 6.1, 2009 Microsoft Corporation.
See this image and copyright information in PMC

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