Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comment
. 2023 Sep;20(9):580.
doi: 10.1038/s41569-023-00910-1.

Ruxolitinib is a CaMKII inhibitor that can be repurposed to prevent arrhythmias

Karina Huynh  1
Affiliations
Comment

Ruxolitinib is a CaMKII inhibitor that can be repurposed to prevent arrhythmias

Karina Huynh. Nat Rev Cardiol. 2023 Sep.
No abstract available

PubMed Disclaimer

Comment on

  • An improved reporter identifies ruxolitinib as a potent and cardioprotective CaMKII inhibitor.
    Reyes Gaido OE, Pavlaki N, Granger JM, Mesubi OO, Liu B, Lin BL, Long A, Walker D, Mayourian J, Schole KL, Terrillion CE, Nkashama LJ, Hulsurkar MM, Dorn LE, Ferrero KM, Huganir RL, Müller FU, Wehrens XHT, Liu JO, Luczak ED, Bezzerides VJ, Anderson ME. Reyes Gaido OE, et al. Sci Transl Med. 2023 Jun 21;15(701):eabq7839. doi: 10.1126/scitranslmed.abq7839. Epub 2023 Jun 21. Sci Transl Med. 2023. PMID: 37343080 Free PMC article.

References

Original article
    1. Reyes Gaido, O. E. et al. An improved reporter identifies ruxolitinib as a potent and cardioprotective CaMKII inhibitor. Sci. Transl. Med. 15, eabq7839 (2023) - DOI - PubMed
Related article
    1. Abdelsayed, M. et al. Repurposing drugs to treat cardiovascular disease in the era of precision medicine. Nat. Rev. Cardiol. 19, 751–764 (2022) - DOI - PubMed - PMC

LinkOut - more resources