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Case Reports
. 2023 Dec;39(12):3435-3443.
doi: 10.1007/s00381-023-06054-4. Epub 2023 Jul 4.

Endoscope-assisted microsurgical resection of a third ventricular immature teratoma

Ehab El Refaee  1   2 , Steffen Fleck  3 , Marc Matthes  3 , Holger Lode  4 , Silke Vogelgesang  5 , Henry W S Schroeder  3
Affiliations
Case Reports

Endoscope-assisted microsurgical resection of a third ventricular immature teratoma

Ehab El Refaee et al. Childs Nerv Syst. 2023 Dec.

Abstract

Background: Reaching a tumor within the third ventricle is challenging, and planning an accessible trajectory is crucial without injuring the surrounding structures. We report a 5-year-old boy presented with headache and a seizure where sequential MRI brain studies in a short time period revealed a rapid growing immature teratoma within the third ventricle with hydrocephalic changes. Several management procedures were performed for CSF diversion and medical treatment of the tumor with chemotherapy and stem cell therapy. The tumor was rapidly growing, and surgical excision was decided. Total resection was achieved via endoscope-assisted microsurgical transcallosal approach. Seven years after surgery, the patient experienced no recurrence of the tumor with a favorable clinical condition.

Conclusion: We report a rare case of posterior third ventricular immature teratoma where the endoscope-assisted microsurgical technique was implemented with favorable long-term postoperative outcome.

Keywords: Endoscope-assisted; Foramen of Monro; Immature teratoma; Third ventricle; Transcallosal approach.

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References

    1. Siwanuwatn R, Deshmukh P, Feiz-Erfan I et al (2005) Microsurgical anatomy of the transcallosal anterior interforniceal approach to the third ventricle. Neurosurgery 56:390–6 - PubMed
    1. Kasowski HJ, Nahed BV, Piepmeier JM (2005) Transcallosal transchoroidal approach to tumors of the third ventricle. Neurosurgery 57:361–6 - PubMed
    1. Fonseca A, Faure-Conter C, Murray MJ et al (2022) Pattern of treatment failures in patients with central nervous system non-germinomatous germ cell tumors (CNS-NGGCT): A pooled analysis of clinical trials. Neuro Oncol 24:1950–1961 - DOI - PubMed - PMC
    1. Hu X, Ren Y-M, Yang X et al (2022) Surgical Treatment of pineal region tumors: 18 years experience at a Single Institution. World Neurosurg. https://doi.org/10.1016/j.wneu.2022.09.091 - DOI - PubMed
    1. Kanamori M, Kumabe T, Tominaga T (2008) Is histological diagnosis necessary to start treatment for germ cell tumours in the pineal region? J Clin Neurosci 15:978–987 - DOI - PubMed

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