Inflammatory profile in mitochondrial diseases: A cohort study

Guido Primiano^{1

2}, Domenico Plantone³, Geny Piro⁴, Carmine Carbone⁴, Andrea Sabino², Cristina Sancricca^{1

5}, Michela Di Nottia⁶, Rosalba Carrozzo⁶, Serenella Servidei^{1

2}

Affiliations

¹ Dipartimento di Neuroscienze, Organi di Senso e Torace, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy.
² Dipartimento Di Neuroscienze, Università Cattolica del Sacro Cuore, Rome, Italy.
³ Department of Medicine, Surgery and Neuroscience, University of Siena, Siena, Italy.
⁴ Department of Medical and Surgical Sciences, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy.
⁵ Fondazione UILDM Lazio Onlus, Rome, Italy.
⁶ Unit of Cellular Biology and Mitochondrial Disease, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy.

Guido Primiano et al. Eur J Neurol. 2023 Oct.

. 2023 Oct;30(10):3409-3410.

doi: 10.1111/ene.15962. Epub 2023 Jul 16.

Guido Primiano^{1

2}, Domenico Plantone³, Geny Piro⁴, Carmine Carbone⁴, Andrea Sabino², Cristina Sancricca^{1

5}, Michela Di Nottia⁶, Rosalba Carrozzo⁶, Serenella Servidei^{1

2}

¹ Dipartimento di Neuroscienze, Organi di Senso e Torace, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy.
² Dipartimento Di Neuroscienze, Università Cattolica del Sacro Cuore, Rome, Italy.
³ Department of Medicine, Surgery and Neuroscience, University of Siena, Siena, Italy.
⁴ Department of Medical and Surgical Sciences, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy.
⁵ Fondazione UILDM Lazio Onlus, Rome, Italy.
⁶ Unit of Cellular Biology and Mitochondrial Disease, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy.

No abstract available

References

1. Marchi S, Guilbaud E, Tait SWG, Yamazaki T, Galluzzi L. Mitochondrial control of inflammation. Nat Rev Immunol. 2023;23(3):159-173. doi:10.1038/s41577-022-00760-x
1. Zhang Q, Raoof M, Chen Y, et al. Circulating mitochondrial DAMPs cause inflammatory responses to injury. Nature. 2010;464(7285):104-107. doi:10.1038/nature08780
1. Moya GE, Rivera PD, Dittenhafer-Reed KE. Evidence for the role of mitochondrial DNA release in the inflammatory response in neurological disorders. Int J Mol Sci. 2021;22(13):7030. doi:10.3390/ijms22137030
1. Liu T, Zhang L, Joo D, Sun SC. NF-κB signaling in inflammation. Signal Transduct Target Ther. 2017;2:17023. doi:10.1038/sigtrans.2017.23
1. Tanaka T, Narazaki M, Kishimoto T. IL-6 in inflammation, immunity, and disease. Cold Spring Harb Perspect Biol. 2014;6(10):a016295. doi:10.1101/cshperspect.a016295