Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2023 Jun;55(2):158-164.
doi: 10.5152/eurasianjmed.2023.53.

The Frequency of Association of Nail Involvement and Psoriatic Arthritis in Psoriasis Patients

Erdal Pala  1 , Mehmet Melikoğlu  1 , Ömer Karaşahin  2 , Meltem Alkan Melikoğlu  3
Affiliations

The Frequency of Association of Nail Involvement and Psoriatic Arthritis in Psoriasis Patients

Erdal Pala et al. Eurasian J Med. 2023 Jun.

Abstract

Objective: While the relationship between psoriatic arthritis and skin findings is well-known in patients with psoriasis, the relationship between psoriatic arthritis and nail involvement is less known. In this study, it was aimed to examine the frequency of association between nail involvement and psoriatic arthritis in patients with psoriasis.

Materials and methods: Our study is a retrospective observational study. It was conducted with 250 regis- tered patients who applied to the dermatology polyclinic and clinic of our university hospital. The follow-up forms of the patients were scanned retrospectively and the findings were recorded.

Results: The average age of the 250 patients evaluated in this study was 39.62 ± 9.30, and 133 (53.2%) of them were women. The frequency of nail involvement in psoriasis patients was determined to be 36.8% (n=92) and the frequency of arthritis was determined to be 8.8% (n=22). Nail involvement was statisti- cally significantly more common in those with arthritis, and nail involvement was present in all of those with arthritis (P < .001). Nail involvement was significantly more common in those with only arthralgia (P < .001). A significantly higher average of nail psoriasis severity index was found in those with both joint and nail involvement compared to those with only nail involvement (P < .001). There was no statistically significant difference in terms of psoriasis area severity index average (P=.235). Proximal and distal interphalangeal arthralgia and sacroiliac arthralgia were found significantly more frequently in those with nail involvement than in those without nail involvement (respectively P = .007 and P < .001). There was no statistically signifi- cant relationship between nail involvement with the presence of arthritis and the clinical type (respectively P = .288 and P = .955).

Conclusion: Joint involvement and nail involvement in patients with psoriasis are closely related, and we think that nail and joint involvement in psoriasis patients should be evaluated together.

PubMed Disclaimer

Figures

Figure 1.
Figure 1.
The relationship between nail involvement and arthritis and arthralgia.
Figure 2.
Figure 2.
Average values of PASI and NAPSI according to nail and joint involvement.
Figure 3.
Figure 3.
The distribution of clinical types according to the presence of nail and joint involvement in psoriasis.
See this image and copyright information in PMC

Similar articles

See all similar articles

Cited by

References

    1. Soy M, Karaca N, Umit EU, Bes C, Piskin S. Joint and nail involvement in Turkish patients with psoriatic arthritis. Rheumatol Int. 2008;29(2):223 225. (10.1007/s00296-008-0686-5) - DOI - PubMed
    1. Ritchlin CT, Colbert RA, Gladman DD. Psoriatic arthritis. N Engl J Med. 2017;376(10):957 970. (10.1056/NEJMra1505557) - DOI - PubMed
    1. Langenbruch A, Radtke MA, Krensel M, Jacobi A, Reich K, Augustin M. Nail involvement as a predictor of concomitant psoriatic arthritis in patients with psoriasis. Br J Dermatol. 2014;171(5):1123 1128. (10.1111/bjd.13272) - DOI - PubMed
    1. Gladman DD. Psoriatic arthritis. In: Harris E, Budd R, Freistein G, eds. Kelly’s Textbook of Rheumatology. 7th ed. Philadelphia: Elsevier Saunders; 2005:1156 1164.
    1. Bruce IN. Psoriatic arthritis: clinical features. In: Hochberg MC, Silman AJ, Smolen JS, Weinblat ME, Weisman MH, eds. Rheumatology. 4th ed. Philadelphia: Elsevier Limited; 2008:1165 1176.

LinkOut - more resources