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. 2023 Nov-Dec;39(6):e176-e179.
doi: 10.1097/IOP.0000000000002425. Epub 2023 Jul 4.

Severe Mpox Infection of the Eye and Periocular Region

Affiliations

Severe Mpox Infection of the Eye and Periocular Region

Colin Bacorn et al. Ophthalmic Plast Reconstr Surg. 2023 Nov-Dec.

Abstract

Mpox is an emerging zoonotic infection with potentially severe ocular and periocular consequences, particularly in immunocompromised patients. This report summarizes 2 cases of fulminant mpox presenting in patients with AIDS. In the first case, confluent lesions resulted in orbital compartment syndrome and total eyelid necrosis. In the second case, eyelid involvement was accompanied by corneal melt and perforation. Despite aggressive medical and surgical treatment, both patients developed permanent loss of vision and ultimately expired.

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Conflict of interest statement

The authors have no financial or conflicts of interest to disclose.

References

    1. Kumar N, Acharya A, Gendelman HE, et al. The 2022 outbreak and the pathobiology of the monkeypox virus. J Autoimmun. 2022;131:102855.
    1. Cash-Goldwasser S, Labuda SM, McCormick DW, et al.; CDC Monkeypox Clinical Escalations Team. Ocular Monkeypox — United States, July–September 2022. MMWR Morb Mortal Wkly Rep. 2022;71:1343–1347.
    1. Sah R, Mohanty A, Abdelaal A, et al. First Monkeypox deaths outside Africa: no room for complacency. Ther Adv Infect Dis. 2022;9:20499361221124028.
    1. Bayer-Garner IB. Monkeypox virus: histologic, immunohistochemical and electron-microscopic findings. J Cutan Pathol. 2005;32:28–34.
    1. Chalali F, Merlant M, Truong A, et al. Histological features associated with Human Monkeypox Virus Infection in 2022 outbreak in a non-endemic country. Clin Infect Dis. 2023;76:1132–1135.