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. 2023 Jul;17(7):663-671.
doi: 10.1111/crj.13653. Epub 2023 Jul 5.

Risk factors for the recurrence in pulmonary tuberculosis patients with massive hemoptysis

Qiong Lin  1 , Jian Chen  2 , Tianxing Yu  1 , Bing Gao  3 , Kaijin Kuang  4 , Yong Fan  5 , Junping Xu  1 , Xiaohua Li  1 , Xin Lin  1 , Liyu Xu  1
Affiliations

Risk factors for the recurrence in pulmonary tuberculosis patients with massive hemoptysis

Qiong Lin et al. Clin Respir J. 2023 Jul.

Abstract

Objectives: To evaluate the outcomes of bronchial artery embolization (BAE) for the treatment of massive hemoptysis in patients with pulmonary tuberculosis and identify risk factors that influence recurrence.

Methods: A total of 81 patients with massive hemoptysis who underwent BAE between January 2014 and December 2017 were retrospectively reviewed. All of the patients had either a history of pulmonary tuberculosis or a current diagnosis of pulmonary tuberculosis. Follow-up ranged from 18 to 66 months.

Results: Hemoptysis was stopped or markedly decreased, with subsequent clinical improvement in 73 patients, while 11 patients experienced recurrence during the follow-up period. Systemic-pulmonary shunts and clinical failure showed a statistically significant correlation with the recurrence rate. The cumulative non-recurrence rate was 95.3% for 3 months and 81.9% for more than 24 months. Complications were common (12.5%), but self-limiting.

Conclusions: BAE is a safe and effective treatment option for the control of massive hemoptysis in pulmonary tuberculosis patients. Systemic-pulmonary shunts and clinical failure are the risk factors for recurrence.

Keywords: embolization; massive hemoptysis; prognosis; pulmonary tuberculosis.

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Conflict of interest statement

The authors declare that they have no competing interests.

Figures

FIGURE 1
FIGURE 1
The cumulative hemoptysis control rate as depicted by the Kaplan–Meier method. BAE, bronchial artery embolization.
FIGURE 2
FIGURE 2
The cumulative hemoptysis control rate as depicted by the Kaplan–Meier method: p = 0.013; clinical success versus clinical failure. BAE, bronchial artery embolization.
FIGURE 3
FIGURE 3
The cumulative hemoptysis control rate as depicted by the Kaplan–Meier method: p = 0.035; shunt (−) versus shunt (+). BAE, bronchial artery embolization.
See this image and copyright information in PMC

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