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Comment
. 2023 Jul;619(7968):E19-E23.
doi: 10.1038/s41586-023-06270-7.

Reply to: DHODH inhibitors sensitize to ferroptosis by FSP1 inhibition

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Comment

Reply to: DHODH inhibitors sensitize to ferroptosis by FSP1 inhibition

Chao Mao et al. Nature. 2023 Jul.
No abstract available

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References

    1. Dixon, S. J. et al. Ferroptosis: an iron-dependent form of nonapoptotic cell death. Cell 149, 1060–1072 (2012). - DOI - PubMed - PMC
    1. Stockwell, B. R. Ferroptosis turns 10: emerging mechanisms, physiological functions, and therapeutic applications. Cell 185, 2401–2421 (2022). - DOI - PubMed
    1. Mao, C. et al. DHODH-mediated ferroptosis defence is a targetable vulnerability in cancer. Nature 593, 586–590 (2021). - DOI - PubMed - PMC
    1. Mishima, E. et al. DHODH inhibitors sensitize to ferroptosis by FSP1 inhibition. Nature https://doi.org/10.1038/s41586-023-06269-0 (2023).
    1. Bersuker, K. et al. The CoQ oxidoreductase FSP1 acts parallel to GPX4 to inhibit ferroptosis. Nature 575, 688–692 (2019). - DOI - PubMed - PMC

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