The Y chromosome as a risk factor

Anna Dart¹

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Comment

Anna Dart. Nat Rev Cancer. 2023 Aug.

. 2023 Aug;23(8):511.

doi: 10.1038/s41568-023-00605-2.

Anna Dart¹

No abstract available

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Y chromosome loss in cancer drives growth by evasion of adaptive immunity.
Abdel-Hafiz HA, Schafer JM, Chen X, Xiao T, Gauntner TD, Li Z, Theodorescu D. Abdel-Hafiz HA, et al. Nature. 2023 Jul;619(7970):624-631. doi: 10.1038/s41586-023-06234-x. Epub 2023 Jun 21. Nature. 2023. PMID: 37344596 Free PMC article.
Histone demethylase KDM5D upregulation drives sex differences in colon cancer.
Li J, Lan Z, Liao W, Horner JW, Xu X, Liu J, Yoshihama Y, Jiang S, Shim HS, Slotnik M, LaBella KA, Wu CJ, Dunner K Jr, Hsu WH, Lee R, Khanduri I, Terranova C, Akdemir K, Chakravarti D, Shang X, Spring DJ, Wang YA, DePinho RA. Li J, et al. Nature. 2023 Jul;619(7970):632-639. doi: 10.1038/s41586-023-06254-7. Epub 2023 Jun 21. Nature. 2023. PMID: 37344599 Free PMC article.

1. Li, J. et al. Histone demethylase KDM5D upregulation drives sex differences in colon cancer. Nature https://doi.org/10.1038/s41586-023-06254-7 (2023) - DOI - PubMed - PMC
1. Abdel-Hafiz, H. A. et al. Y chromosome loss in cancer drives growth by evasion of adaptive immunity. Nature https://doi.org/10.1038/s41586-023-06234-x (2023) - DOI - PubMed

1. Qi, M. et al. Loss of chromosome Y in primary tumors. Cell https://doi.org/10.1016/j.cell.2023.06.006 (2023) - DOI - PubMed