Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2023 Jun 5;15(6):e40006.
doi: 10.7759/cureus.40006. eCollection 2023 Jun.

It Comes and Goes: Pediatric Chronic Spontaneous Urticaria

Affiliations
Case Reports

It Comes and Goes: Pediatric Chronic Spontaneous Urticaria

Ming Lee Chin. Cureus. .

Abstract

Chronic spontaneous urticaria (CSU) is an underrecognized and underreported condition, even more so in the pediatric population. Due to its fugacious nature, the period between the onset of symptoms and the diagnosis of CSU is often long. We discuss the case of a 10-year-old child who presented with a six-month history of recurrent, pruritic rash. Medical advice was sought on multiple occasions; however, no treatment was initiated. This resulted in the child and caretakers becoming increasingly worried. The child was subsequently diagnosed with CSU. Daily second-generation antihistamine was started, and the child responded well with marked improvement of symptoms. Our case raises a pertinent point. It is crucial for physicians to be able to recognize and treat CSU according to evidence-based guidelines, as this condition may not only negatively affect the child's quality of life, but its impact also extends to the caretakers.

Keywords: antihistamine; chronic spontaneous urticaria; chronic urticaria; omalizumab; pediatric dermatology.

PubMed Disclaimer

Conflict of interest statement

The authors have declared that no competing interests exist.

Figures

Figure 1
Figure 1. Urticaria over the child’s bilateral lower limbs.
Figure 2
Figure 2. Close-up of urticaria on the child’s leg.

References

    1. Pediatric chronic spontaneous urticaria: a brief clinician's guide. Votto M, Achilli G, De Filippo M, et al. Expert Rev Clin Immunol. 2022;18:889–899. - PubMed
    1. The burden of chronic spontaneous urticaria is substantial: real-world evidence from ASSURE-CSU. Maurer M, Abuzakouk M, Bérard F, et al. Allergy. 2017;72:2005–2016. - PMC - PubMed
    1. The international EAACI/GA²LEN/EuroGuiDerm/APAAACI guideline for the definition, classification, diagnosis, and management of urticaria. Zuberbier T, Abdul Latiff AH, Abuzakouk M, et al. Allergy. 2022;77:734–766. - PubMed
    1. Management of pediatric chronic spontaneous urticaria: a review of current evidence and guidelines. Chang J, Cattelan L, Ben-Shoshan M, Le M, Netchiporouk E. J Asthma Allergy. 2021;14:187–199. - PMC - PubMed
    1. Management of chronic urticaria in children: a clinical guideline. Caffarelli C, Paravati F, El Hachem M, et al. Ital J Pediatr. 2019;45:101. - PMC - PubMed

Publication types

LinkOut - more resources