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Case Reports
. 2023 Jun 5;15(6):e39999.
doi: 10.7759/cureus.39999. eCollection 2023 Jun.

Penile Glans Necrosis Associated With Antiphospholipid Syndrome: A Rare Complication

Affiliations
Case Reports

Penile Glans Necrosis Associated With Antiphospholipid Syndrome: A Rare Complication

Minh H Truong et al. Cureus. .

Abstract

Penile glans necrosis is a rare clinical condition caused by trauma, diabetes mellitus, adverse effect of vasoconstrictive solutions, and circumcision. Antiphospholipid syndrome (APS) is categorized as an autoimmune disease with the presence of antiphospholipid antibodies that results in an increased risk of vascular thrombosis and obstetrical complications. In this article, we report a rare case of a 20-year-old boy with penile glans necrosis due to penile vascular thrombosis following catastrophic antiphospholipid syndrome (CAPS) which we successfully treated at People's Hospital 115.

Keywords: antiphospholipid syndrome; catastrophic antiphospholipid syndrome (caps); ischemia of the penis; penile glans necrosis; penile reconstructive surgery.

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Conflict of interest statement

The authors have declared that no competing interests exist.

Figures

Figure 1
Figure 1. The necrosis of the glans penis on the 14th day of the disease
Figure 2
Figure 2. The penis after the first reconstructive surgery with urethral reconstruction and burying the penis into the penile healthy skin left and the scrotum
Figure 3
Figure 3. The penis after eliminating the glans necrosis
Figure 4
Figure 4. Modified Lipszyc technique for the buried penis
Figure 5
Figure 5. Pubic lipectomy and cutting of the suspensory ligament of the penis
Figure 6
Figure 6. The penis after the second stage of reconstructive surgery
Figure 7
Figure 7. The penis after completely reconstructive procedures in the flaccid state
Figure 8
Figure 8. The penis after completely reconstructive procedures in the erection

References

    1. Penile glans necrosis following penile sclerosing lipogranuloma repair: a rare case. Soebhali B. Bali Medical Journal. 2019;8:944–946.
    1. The surgical management of ischemic penile gangrene in diabetics with end-stage atherosclerosis. Weiner DM, Lowe FC. J Urol. 1996;155:926–929. - PubMed
    1. Long-term follow-up of penile glans necrosis due to paraphimosis. Sato Y, Takagi S, Uchida K, et al. IJU Case Rep. 2019;2:171–173. - PMC - PubMed
    1. Penile glans necrosis following prostatic artery embolization for the treatment of benign prostatic hyperplasia: a rare but serious complication. Chung E. Case Rep Urol. 2021;2021:6662899. - PMC - PubMed
    1. Antiphospholipid syndrome: advances in diagnosis, pathogenesis, and management. Knight JS, Branch DW, Ortel TL. BMJ. 2023;380:0. - PubMed

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