Vaginal Natural Orifice Transluminal Endoscopic Surgery in a Second-trimester Pregnant Woman with an Ovarian Teratoma
- PMID: 37416106
- PMCID: PMC10321348
- DOI: 10.4103/gmit.gmit_107_22
Vaginal Natural Orifice Transluminal Endoscopic Surgery in a Second-trimester Pregnant Woman with an Ovarian Teratoma
Abstract
We present the first case of a pregnant woman with teratoma, who underwent vaginal natural orifice transluminal endoscopic surgery (vNOTES). Mature ovarian cystic teratomas compromise 20%-30% of all ovarian tumors. The best surgical management is still unclear, especially during pregnancy. A 21-year-old pregnant woman (gravida 1, para 0) at 14 weeks and 3 days of gestational age was admitted with an intermittent mild sharp and dull pain in her right lower abdomen when walking or moving lower limbs. Pelvic ultrasonography revealed a 5.9 cm × 5.4 cm heterogeneous mass that was suspected as a teratoma in the right adnexa. Initially, laparoendoscopic single-site ovarian cystectomy (OC) was arranged. However, the ovarian tumor was impeded by the enlarged uterus. The OC procedure was changed to vNOTES OC. The vNOTES OC was performed smoothly and the pathology confirmed the mass to be a teratoma. After the operation, she recovered well and was discharged 2 days after the operation without any complication. In conclusion, the application of vNOTES in the second-trimester pregnancy might be considered safe and effective. The vNOTES can be performed safely in selected patients and by an experienced surgeon.
Keywords: Laparoscopy; natural orifice transluminal endoscopic surgery; pregnancy; teratoma.
Copyright: © 2023 Gynecology and Minimally Invasive Therapy.
Conflict of interest statement
Prof. Dah-Ching Ding, an editorial board member at Gynecology and Minimally Invasive Therapy, had no role in the peer review process of or decision to publish this article. The other author declared no conflicts of interest in writing this paper.
Figures

Similar articles
-
Transvaginal natural orifice transluminal endoscopic surgery-assisted versus transumbilical laparoendoscopic single-site ovarian cystectomy for ovarian mature cystic teratoma. A randomized controlled trial.Ginekol Pol. 2024;95(5):343-349. doi: 10.5603/gpl.95422. Epub 2023 Dec 15. Ginekol Pol. 2024. PMID: 38099663 Clinical Trial.
-
Comparative analysis of vaginal natural orifice transluminal endoscopic surgery versus transumbilical laparoendoscopic single-site surgery in ovarian cystectomy.J Obstet Gynaecol Res. 2021 Feb;47(2):757-764. doi: 10.1111/jog.14603. Epub 2020 Dec 16. J Obstet Gynaecol Res. 2021. PMID: 33331001
-
Transvaginal natural orifice transluminal endoscopic surgery: a new approach to ovarian cystectomy.Fertil Steril. 2018 Feb;109(2):366. doi: 10.1016/j.fertnstert.2017.10.037. Epub 2017 Dec 13. Fertil Steril. 2018. PMID: 29246560
-
Transvaginal natural orifice transluminal endoscopic surgery (vNOTES) in gynecologic surgeries: A systematic review.Asian J Surg. 2020 Jan;43(1):44-51. doi: 10.1016/j.asjsur.2019.07.014. Epub 2019 Aug 20. Asian J Surg. 2020. PMID: 31444108
-
Comparison of Outcomes following Vaginal Natural Orifice Transluminal Endoscopic Surgery and Laparoendoscopic Single-site Surgery in Benign Hysterectomy: A Systematic Review and Meta-analysis.Gynecol Minim Invasive Ther. 2023 Sep 7;12(4):195-202. doi: 10.4103/gmit.gmit_88_22. eCollection 2023 Oct-Dec. Gynecol Minim Invasive Ther. 2023. PMID: 38034107 Free PMC article. Review.
Cited by
-
Clinical efficacy and safety study of vNOTES for benign ovarian tumors in obese patients.Sci Rep. 2025 Feb 7;15(1):4609. doi: 10.1038/s41598-025-88599-9. Sci Rep. 2025. PMID: 39920195 Free PMC article.
References
-
- Webb KE, Sakhel K, Chauhan SP, Abuhamad AZ. Adnexal mass during pregnancy:A review. Am J Perinatol. 2015;32:1010–6. - PubMed
-
- Ahmed A, Lotfollahzadeh S. StatPearls. Treasure Island (FL): StatPearls Publishing; 2022. Cystic Teratoma. - PubMed
-
- Baekelandt J. Transvaginal natural orifice transluminal endoscopic surgery:A new approach to ovarian cystectomy. Fertil Steril. 2018;109:366. - PubMed
Publication types
LinkOut - more resources
Full Text Sources