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. 2023 Jul;71(7):2911-2912.
doi: 10.4103/IJO.IJO_872_23.

Insulin eye drops for neurotrophic keratitis

Affiliations

Insulin eye drops for neurotrophic keratitis

Mayur R Moreker et al. Indian J Ophthalmol. 2023 Jul.
No abstract available

Keywords: Corneal Ulcer; Insulin eye drops; Neurotrophic Keratitis.

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Conflict of interest statement

None

Figures

Figure 1
Figure 1
(a) Right eye of a 55-year-old gentleman with Grade IV neurotrophic keratitis. (b) Right eye of a 55-year-old gentleman with Grade IV neurotrophic keratitis, 12 days after use of insulin eye drops. (c) Right eye of a 55-year-old gentleman with Grade IV neurotrophic keratitis, 25 days after use of Insulin eye drops
Figure 2
Figure 2
(a) Right eye of a 41-year-old gentleman, diabetic patient, with post-COVID mucormycosis at presentation. (b) Right eye of a 41-year-old gentleman, diabetic patient, with post-COVID mucormycosis that developed NK despite an initial temporary tarsorrhaphy with intense lubrication. (c) Right eye of a 41-year-old gentleman, diabetic patient, with post-COVID mucormycosis with partial resolution after a permanent tarsorrhaphy and amniotic membrane transplantation. (d) Right eye of a 41-year-old gentleman, diabetic patient, with post-COVID mucormycosis with the resolution of congestion and a stable ocular surface, after the introduction of insulin eye drops

References

    1. Wang AL, Weinlander E, Metcalf BM, Barney NP, Gamm DM, Nehls SM, et al. Use of topical insulin to treat refractory neurotrophic corneal ulcers. Cornea. 2017;36:1426–8. - PMC - PubMed
    1. Galvis V, Niño CA, Tello A, Grice JM, Gomez MA. Topical insulin in neurotrophic keratopathy after resection of acoustic neuroma. Arch Soc Esp Oftalmol. 2019;94:100–4. - PubMed
    1. Bastion ML, Ling KP. Topical insulin for healing of diabetic epithelial defects: A retrospective review of corneal debridement during vitreoretinal surgery in Malaysian patients. Med J Malaysia. 2013;68:208–16. - PubMed
    1. Rocha EM, Cunha DA, Carneiro EM, Boschero AC, Saad MJ, Velloso LA. Identification of insulin in the tear film and insulin receptor and IGF-1 receptor on the human ocular surface. Invest Ophthalmol Vis Sci. 2002;43:963–7. - PubMed
    1. Bartlett JD, Turner-Henson A, Atchison JA, Woolley TW, Pillion DJ. Insulin administration to the eyes of normoglycemic human volunteers. J Ocul Pharmacol. 1994;10:683–90. - PubMed