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. 2023 Jul;30(4):377-383.
doi: 10.1007/s40292-023-00591-4. Epub 2023 Jul 7.

Inter-Arm Blood Pressure Difference an Indicator of Coronary Artery Disease

Hanna K Al-Makhamreh  1 , Abdulhak A Sadalla  2 , Hussein Alhawari  3 , Adees W Bedros  4   5 , Maher M Kahlous  6   5 , Mohammed A Amer  7   5 , Baraa A Al-Mubarak  5 , Moaiad Hussein  5 , Ahmad A Toubasi  8 , Hayder T Chichan  5
Affiliations

Inter-Arm Blood Pressure Difference an Indicator of Coronary Artery Disease

Hanna K Al-Makhamreh et al. High Blood Press Cardiovasc Prev. 2023 Jul.

Abstract

Introduction: Considering the scarcity of the literature on the association between inter-arms blood pressure difference (IABPD) and coronary artery disease (CAD).

Aim: We performed this study to investigate the prevalence of IABPD within the Jordanian population and to assess if it has an association with CAD.

Methods: We sampled patients visiting the cardiology clinics at the Jordan University Hospital between October, 2019 and October 2021 into two groups. Participants were divided into two groups; patients with severe CAD and control group who had no evidence of CAD.

Results: We measured the blood pressure for a total of 520 patients. Of the included patients, 289 (55.6 %) had CAD while 231 (44.4%) were labeled as controls who were normal. A total of 221 (42.5%) participants had systolic IABPD above 10 mmHg, while 140 (26.9%) had a diastolic IABPD above 10 mmHg. Univariate analysis demonstrated that patients with CAD were significantly more likely to be older (p < 0.001), of the male gender (p < 0.001), hypertensive (p < 0.001), and having dyslipidemia (p < 0.001). Moreover, they had significantly higher IABPD differences in terms of both systolic and diastolic blood pressure (p < 0.001 and p = 0.022, respectively). Multivariate analysis showed that CAD was a positive predictor of abnormal systolic IABPD.

Conclusion: In our study, elevated systolic IABPD was associated with a higher prevalence of severe CAD. Patients with abnormal IABPD might be subjected to more specialist investigation as IABPD consistently predicts coronary artery disease, peripheral arterial disease or other vasculopathy throughout the literature.

Keywords: Blood pressure; CAD; IHD; Inter-arm blood pressure difference.

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