Regulation of developmental tempo in different vertebrate species
- PMID: 37419101
- DOI: 10.1016/j.stem.2023.06.001
Regulation of developmental tempo in different vertebrate species
Abstract
In this issue, Lazaro et al.1 use iPSC-derived presomitic mesoderm cells to analyze the oscillatory expression of somitic clock genes. Comparison of a wide range of species, including mouse, rabbit, cattle, rhinoceros, human, and marmoset, demonstrates an excellent correlation between biochemical reaction speed and the tempo of the clock.
Copyright © 2023 Elsevier Inc. All rights reserved.
Conflict of interest statement
Declaration of interests The author declares no competing interests.
Comment on
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A stem cell zoo uncovers intracellular scaling of developmental tempo across mammals.Cell Stem Cell. 2023 Jul 6;30(7):938-949.e7. doi: 10.1016/j.stem.2023.05.014. Epub 2023 Jun 20. Cell Stem Cell. 2023. PMID: 37343565 Free PMC article.
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