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Review
. 2023 Aug;34(3):563-572.
doi: 10.1016/j.pmr.2023.04.003. Epub 2023 Apr 18.

Autonomic Dysfunction Related to Postacute SARS-CoV-2 Syndrome

Justin Haloot  1 , Ratna Bhavaraju-Sanka  2 , Jayasree Pillarisetti  3 , Monica Verduzco-Gutierrez  4
Affiliations
Review

Autonomic Dysfunction Related to Postacute SARS-CoV-2 Syndrome

Justin Haloot et al. Phys Med Rehabil Clin N Am. 2023 Aug.

Abstract

Persistence of symptoms beyond the initial acute phase of coronavirus disease-2019 (COVID-19) is termed postacute SARS-CoV-2 (PASC) and includes neurologic, autonomic, pulmonary, cardiac, psychiatric, gastrointestinal, and functional impairment. PASC autonomic dysfunction can present with dizziness, tachycardia, sweating, headache, syncope, labile blood pressure, exercise intolerance, and "brain fog." A multidisciplinary team can help manage this complex syndrome with nonpharmacologic and pharmacologic interventions.

Keywords: Autonomic dysfunction; Brain fog; COVID-19; PASC; Tilt table test.

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Figures

Fig. 1
Fig. 1
Mechanism of post-acute SARS-CoV-2 autonomic dysfunction.
See this image and copyright information in PMC

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References

    1. Halpin S.J., McIvor C., Whyatt G., et al. Postdischarge symptoms and rehabilitation needs in survivors of Covid-19 infection: A cross-sectional evaluation. J Med Virol. 2020;93(2):1013–1022. - PubMed
    1. Huang C, Huang L, Wang Y, et al. 6-Month Consequences of COVID-19 in Patients Discharged from Hospital: A Cohort Study, Lancet, 397 (10270), 2021, 220–232. - PMC - PubMed
    1. Zhu N., Zhang D., Wang W., et al. A novel coronavirus from patients with pneumonia in China, 2019. N Engl J Med. 2020;382:727–733. - PMC - PubMed
    1. Chan J.F., Yuan S., Kok K.H., et al. A familial cluster of pneumonia associated with the 2019 novel coronavirus indicating person-to-person transmission: a study of a family cluster. Lancet. 2020;395:514–523. - PMC - PubMed
    1. Huang C., Wang Y., Li X., et al. Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. Lancet. 2020;395:497–506. - PMC - PubMed