Using gut microorganisms to treat cancer

Y David Seo¹, Nadim Ajami², Jennifer A Wargo^{3

4}

Affiliations

¹ Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
² Platform for Innovative Microbiome and Translational Research, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
³ Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. jwargo@mdanderson.org.
⁴ Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. jwargo@mdanderson.org.

Comment

Y David Seo et al. Nat Med. 2023 Aug.

. 2023 Aug;29(8):1910-1911.

doi: 10.1038/s41591-023-02460-y.

Y David Seo¹, Nadim Ajami², Jennifer A Wargo^{3

4}

¹ Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
² Platform for Innovative Microbiome and Translational Research, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
³ Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. jwargo@mdanderson.org.
⁴ Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. jwargo@mdanderson.org.

No abstract available

Comment on

Fecal microbiota transplantation plus anti-PD-1 immunotherapy in advanced melanoma: a phase I trial.
Routy B, Lenehan JG, Miller WH Jr, Jamal R, Messaoudene M, Daisley BA, Hes C, Al KF, Martinez-Gili L, Punčochář M, Ernst S, Logan D, Belanger K, Esfahani K, Richard C, Ninkov M, Piccinno G, Armanini F, Pinto F, Krishnamoorthy M, Figueredo R, Thebault P, Takis P, Magrill J, Ramsay L, Derosa L, Marchesi JR, Parvathy SN, Elkrief A, Watson IR, Lapointe R, Segata N, Haeryfar SMM, Mullish BH, Silverman MS, Burton JP, Maleki Vareki S. Routy B, et al. Nat Med. 2023 Aug;29(8):2121-2132. doi: 10.1038/s41591-023-02453-x. Epub 2023 Jul 6. Nat Med. 2023. PMID: 37414899 Clinical Trial.

1. Huang, A. C. & Zappasodi, R. Nat. Immunol. 23, 660–670 (2022). - DOI - PubMed - PMC
1. Morad, G., Helmink, B. A., Sharma, P. & Wargo, J. A. Cell 185, 576 (2022). - DOI - PubMed
1. Routy, B. et al. Nat. Med. https://doi.org/10.1038/s41591-023-02453-x (2023). - DOI - PubMed
1. Feuerstadt, P. et al. New Engl. J. Med. 386, 220–229 (2022). - DOI - PubMed
1. Khanna, S. et al. Drugs 82, 1527–1538 (2022). - DOI - PubMed - PMC