Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2023 Aug;70(1):131-144.
doi: 10.1016/j.yapd.2023.03.001. Epub 2023 May 15.

Lower Urinary Tract Obstruction in Newborns

Affiliations
Review

Lower Urinary Tract Obstruction in Newborns

Jaime Flores-Torres et al. Adv Pediatr. 2023 Aug.

Abstract

Lower urinary tract obstruction (LUTO) is a rare birth defect with a prevalence between 1 in 5,000 and 1 in 25,000 pregnancies. LUTO is one of the most common causes of congenital abnormalities of the renal tract. Several genetic conditions have been associated with LUTO. Most common causes of LUTO are posterior urethral valves and urethral atresia. Despite available prenatal and postnatal treatments, LUTO is a significant cause of morbidity and mortality in newborns causing significant end stage renal disease and pulmonary hypoplasia.

Keywords: End-stage renal disease; Lower urinary tract obstruction; Posterior urethral valves; Prune belly syndrome; Pulmonary hypoplasia; Urethral atresia.

PubMed Disclaimer

LinkOut - more resources