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Editorial
. 2023 Jun 26;8(6):675-676.
doi: 10.1016/j.jacbts.2023.01.014. eCollection 2023 Jun.

Platelet-Derived Growth Factors: A New Therapeutic Opportunity for Treating Cardiac Fibrosis?

Alan J Mouton  1
Affiliations
Editorial

Platelet-Derived Growth Factors: A New Therapeutic Opportunity for Treating Cardiac Fibrosis?

Alan J Mouton. JACC Basic Transl Sci. .
No abstract available

Keywords: fibroblast; fibrosis; myocardial infarction; platelet-derived growth factor.

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Conflict of interest statement

The author has reported that he has no relationships relevant to the contents of this paper to disclose.

Figures

None
Graphical abstract
See this image and copyright information in PMC

Comment on

  • doi: 10.1016/j.jacbts.2022.11.006

References

    1. Venugopal H., Hanna A., Humeres C., Frangogiannis N.G. Properties and functions of fibroblasts and myofibroblasts in myocardial infarction. Cells. 2022;11(9):1386. - PMC - PubMed
    1. Travers J.G., Tharp C.A., Rubino M., McKinsey T.A. Therapeutic targets for cardiac fibrosis: from old school to next-gen. J Clin Invest. 2022;132(5) - PMC - PubMed
    1. Hume R.D., Deshmukh T., Doan T., et al. PDGF-AB reduces myofibroblast differentiation without increasing proliferation after myocardial infarction. J Am Coll Cardiol Basic Trans Science. 2023;8(6):658–674. - PMC - PubMed
    1. Kalra K., Eberhard J., Farbehi N., Chong J.J., Xaymardan M. Role of PDGF-A/B ligands in cardiac repair after myocardial infarction. Front Cell Dev Biol. 2021;9 - PMC - PubMed
    1. Thavapalachandran S., Grieve S.M., Hume R.D., et al. Platelet-derived growth factor-AB improves scar mechanics and vascularity after myocardial infarction. Sci Transl Med. 2020;12(524) - PubMed

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