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. 1986;17(3):289-91.
doi: 10.1007/BF00256702.

The activity of phosphohexose isomerase in primary breast carcinomas and response to chemotherapy in patients with metastatic disease

I Mitchell, N Deshpande, R Millis, R D Rubens

The activity of phosphohexose isomerase in primary breast carcinomas and response to chemotherapy in patients with metastatic disease

I Mitchell et al. Cancer Chemother Pharmacol. 1986.

Abstract

The activity of phosphohexose isomerase [PHI] was measured in 48 primary carcinomas from patients with breast cancer, and its usefulness as a predictor of response to cytotoxic drugs at the metastatic stage was evaluated. There was a statistically significant difference in the activity of PHI between responders and non-responders to these treatments. These preliminary findings are currently being evaluated in an extended series.

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