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. 2023 Jun 7;85(7):3663-3665.
doi: 10.1097/MS9.0000000000000872. eCollection 2023 Jul.

Urinary bladder metastasis from primary lung cancer, a rare and challenging diagnosis: a case report

Mohamed Irzi  1 , Achraf Miri  2 , Anouar El Moudane  3 , Abdelghani Ouraghi  3 , Ali Barki  4
Affiliations

Urinary bladder metastasis from primary lung cancer, a rare and challenging diagnosis: a case report

Mohamed Irzi et al. Ann Med Surg (Lond). .

Abstract

Bladder metastases are rare, representing only 2% of all bladder tumors, secondary bladder localization from a primary lung is exceptional.

Case presentation: The authors describe the case followed for lung adenocarcinoma with an exceptional metastatic site, which is the bladder. A computed tomography scan showed a left suprahilar bronchial tumor with pleurisy (Fig. 1A), which biopsies concluded to a moderately differentiated adenocarcinoma. The patient is treated with palliative cisplatin-based chemotherapy. And died 11 months after diagnosis.

Clinical discussion: Bladder metastases are rare, representing only 2% of all malignant bladder tumors. Metastatic lesions of the bladder are generally revealed by hematuria. Confirmation of bladder invasion is immunohistochemical, facilitated by knowledge of the primitive.

Conclusion: In the presence of any adenocarcinoma of the bladder, a thoracic-abdominal-pelvic computed tomography scan must be requested in search of a primary extra-vesical cancer who can facilitate the diagnosis.

Keywords: hematuria; lung cancer; metastasis to urinary bladder.

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
CT scan showed a suprahilar bronchial tumor.
Figure 2
Figure 2
Presence of a polyp in the bladder.
Figure 3
Figure 3
Photomicrograph showing a carcinomatous proliferation made of moderately atypical cells with frequent formation of lumens and mucin production ( HE, 100×).
Figure 4
Figure 4
Neoplastic cells show expression of CK7.
Figure 5
Figure 5
Neoplastic cells show expression of TTF1.
See this image and copyright information in PMC

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