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. 2023 Jul 10;13(7):e073115.
doi: 10.1136/bmjopen-2023-073115.

What are the prognostic factors for the development of incontinence-associated dermatitis (IAD): a protocol for a systematic review and meta-analysis

Julie Deprez  1   2 , Jan Kottner  2   3 , Alexandra Eilegård Wallin  4 , Nils Ohde  3 , Carina Bååth  5   6 , Ami Hommel  7 , Lisa Hultin  8   9 , Anna Josefson  10   11 , Dimitri Beeckman  4   2
Affiliations

What are the prognostic factors for the development of incontinence-associated dermatitis (IAD): a protocol for a systematic review and meta-analysis

Julie Deprez et al. BMJ Open. .

Abstract

Introduction: Incontinence-associated dermatitis (IAD) is irritant contact dermatitis and skin damage associated with prolonged skin contact with urine and/or faeces. Identifying prognostic factors for the development of IAD may improve management, facilitate prevention and inform future research.

Methods and analysis: This protocol follows the guidelines of the Preferred Reporting Items for Systematic Review and Meta-Analysis Protocols. Prospective and retrospective observational studies or clinical trials in which prognostic factors associated with the development of IAD are described are eligible. There are no restrictions on study setting, time, language, participant characteristics or geographical regions. Reviews, editorials, commentaries, methodological articles, letters to the editor, cross-sectional and case-control studies, and case reports are excluded. MEDLINE, CINAHL, EMBASE and The Cochrane Library will be searched from inception until May 2023. Two independent reviewers will independently evaluate studies. The Quality in Prognostic Studies tool will be used to assess the risk of bias, and the Checklist for Critical Appraisal and Data Extraction for Systematic Reviews of Prediction Modelling Studies-Prognostic Factors checklist will be used for data extraction of the included studies. Separate analyses will be conducted for each identified prognostic factor, with adjusted and unadjusted estimated measures analysed separately. Evidence will be summarised with a meta-analysis when possible, and narratively otherwise. The Q and I2 statistics will be calculated in order to quantify heterogeneity. The quality of the evidence obtained will be evaluated according to the Grades of Recommendation Assessment, Development and Evaluation guidance.

Ethics and dissemination: No ethical approval is needed since all data is already publicly accessible. The results of this work will be published in a peer-reviewed scientific journal.

Keywords: Prognosis; Risk Factors; Systematic Review; WOUND MANAGEMENT.

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Conflict of interest statement

Competing interests: None declared.

References

    1. Beeckman D, Campbell J, Campbell K, et al. . Proceedings of the global IAD expert panel. Incontinence associated dermatitis: moving prevention forward. Wounds International; 2015.
    1. World Health Organization (WHO) . International classification of diseases for mortality and morbidity statistics (11th revision). 2018. Available: https://icd.who.int/browse11/l-m/en [Accessed 09 Jan 2023].
    1. Beeckman D, Van Damme N, Schoonhoven L, et al. . Interventions for preventing and treating incontinence-associated dermatitis in adults. Cochrane Database Syst Rev 2016;11:CD011627. 10.1002/14651858.CD011627.pub2 - DOI - PMC - PubMed
    1. Raepsaet C, Fourie A, Van Hecke A, et al. . Management of incontinence-associated dermatitis: a systematic review of monetary data. Int Wound J 2021;18:79–94. 10.1111/iwj.13496 - DOI - PMC - PubMed
    1. Van den Bussche K, Kottner J, Beele H, et al. . Core outcome domains in incontinence-associated dermatitis research. J Adv Nurs 2018;74:1605–17. 10.1111/jan.13562 - DOI - PubMed

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