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. 1979 Mar;137(3):1088-94.
doi: 10.1128/jb.137.3.1088-1094.1979.

Identification of the ftsA gene product

J F Lutkenhaus, W D Donachie

Identification of the ftsA gene product

J F Lutkenhaus et al. J Bacteriol. 1979 Mar.

Abstract

A nonsense mutation was identified in the essential cell division gene ftsA of Escherichia coli. A gamma-transducing phage was isolated which complemented this mutation. This phage programmed the synthesis of four bacterial proteins in UV-irradiated cells. By substituting the nonsense mutation for the ftsA+ allele in this transducing phage and comparing the proteins programmed by it in UV-treated Su+ and Su- cells, the product of the ftsA gene was identified as a protein with a molecular weight of 50,000.

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References

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