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. 2023 Jul 11;33(1):25.
doi: 10.1038/s41533-023-00344-9.

A systematic review of questionnaires measuring asthma control in children in a primary care population

Sara Bousema  1 , Arthur M Bohnen  2 , Patrick J E Bindels  2 , Gijs Elshout  2
Affiliations

A systematic review of questionnaires measuring asthma control in children in a primary care population

Sara Bousema et al. NPJ Prim Care Respir Med. .

Abstract

Several questionnaires are used to measure asthma control in children. The most appropriate tool for use in primary care is not defined. In this systematic review, we evaluated questionnaires used to measure asthma control in children in primary care and determined their usefulness in asthma management. Searches were performed in the MEDLINE, Embase, Web of Science, Google Scholar and Cochrane databases with end date 24 June 2022. The study population comprised children aged 5-18 years with asthma. Three reviewers independently screened studies and extracted data. The methodological quality of the studies was assessed, using the COSMIN criteria for the measurement properties of health status questionnaires. Studies conducted in primary care were included if a minimum of two questionnaires were compared. Studies in secondary or tertiary care and studies of quality-of-life questionnaires were excluded. Heterogeneity precluded meta-analysis. Five publications were included: four observational studies and one sub-study of a randomized controlled trial. A total of 806 children were included (aged 5-18 years). We evaluated the Asthma Control Test (ACT), childhood Asthma Control Test (c-ACT), Asthma APGAR system, NAEPP criteria and Royal College of Physicians' '3 questions' (RCP3Q). These questionnaires assess different symptoms and domains. The quality of most of the studies was rated 'intermediate' or 'poor'. The majority of the evaluated questionnaires do not show substantial agreement with one another, which makes a comparison challenging. Based on the current review, we suggest that the Asthma APGAR system seems promising as a questionnaire for determining asthma control in children in primary care.

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Conflict of interest statement

The authors declare no competing interests.

Figures

Fig. 1
Fig. 1
Flowchart of the process of identification and inclusion of studies.
See this image and copyright information in PMC

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References

    1. Bush A, Fleming L. Diagnosis and management of asthma in children. BMJ. 2015;350:h996. doi: 10.1136/bmj.h996. - DOI - PubMed
    1. Pols DHJ, Nielen MMJ, Korevaar JC, Bindels PJE, Bohnen AM. Reliably estimating prevalences of atopic children: an epidemiological study in an extensive and representative primary care database. NPJ Prim. Care Respir. Med. 2017;27:23. doi: 10.1038/s41533-017-0025-y. - DOI - PMC - PubMed
    1. Eder W, Ege MJ, von Mutius E. The asthma epidemic. N. Engl. J. Med. 2006;355:2226–2235. doi: 10.1056/NEJMra054308. - DOI - PubMed
    1. Reddel HK, et al. An official American Thoracic Society/European Respiratory Society statement: asthma control and exacerbations: standardizing endpoints for clinical asthma trials and clinical practice. Am. J. Respir. Crit. Care Med. 2009;180:59–99. doi: 10.1164/rccm.200801-060ST. - DOI - PubMed
    1. Taylor DR, et al. A new perspective on concepts of asthma severity and control. Eur. Respir. J. 2008;32:545–554. doi: 10.1183/09031936.00155307. - DOI - PubMed

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