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. 2023 Jul 8;10(7):e01086.
doi: 10.14309/crj.0000000000001086. eCollection 2023 Jul.

Gastric Syphilis: An Unusual Etiology of Melena in a Patient With AIDS

Neelima Gaddipati  1 , Andrew R Scheinberg  2 , Satyapal Chahar  3 , Elizabeth Montgomery  3 , Monica T Garcia-Buitrago  3 , Daniel A Sussman  2
Affiliations

Gastric Syphilis: An Unusual Etiology of Melena in a Patient With AIDS

Neelima Gaddipati et al. ACG Case Rep J. .
No abstract available

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Figures

Figure 1.
Figure 1.
Mildly hyperpigmented discrete macular rash noted on palms.
Figure 2.
Figure 2.
Lesser curvature of the stomach visualized on esophagogastroduodenoscopy. Yellow arrow highlighting linear erosions appearing after insufflation.
Figure 3.
Figure 3.
Immunohistochemistry Treponena pallidum stain of gastric biopsy. T. pallidum spirochete organisms (brown spirochetes highlighted by red arrows) overlying antral and oxyntic mucosa (blue). Mucosa demonstrates severe active erosive chronic gastritis and intestinal metaplasia.
Figure 4.
Figure 4.
Immunohistochemistry Helicobactor pylori stain of gastric biopsy. H. pylori spirochetes noted with red arrows.
See this image and copyright information in PMC

References

    1. Syphilis—STI Treatment Guidelines. Centers for Disease Control and Prevention. (https://www.cdc.gov/std/treatment-guidelines/syphilis.htm). Accessed February 13, 2023.
    1. Greenstein DB, Wilcox CM, Schwartz DA. Gastric Syphilis: Report of seven cases and review of the literature. J Clin Gastroenterol. 1994;18(1):4–9. - PubMed
    1. Mylona EE, Baraboutis IG, Papastamopoulos V, et al. Gastric syphilis: A systematic review of published cases of the last 50 years. Sex Transm Dis. 2010;37(3):177–83. - PubMed