Repair of ultraviolet light-damaged deoxyribonucleic acid in sbc-A strains of Escherichia coli K-12
- PMID: 374357
- PMCID: PMC218244
- DOI: 10.1128/jb.138.1.105-108.1979
Repair of ultraviolet light-damaged deoxyribonucleic acid in sbc-A strains of Escherichia coli K-12
Abstract
An Escherichia coli strain carrying both rec+ and sbcA has been constructed. Repair of ultraviolet light-induced deoxyribonucleic acid damage was examined by measuring survival and thymine-dimer excision in the rec+ sbcA strain as well as rec+ sbcA+ and recB recC sbcA strains. The sbcA mutation restores normal survival in both recB recC uvrB and recB recC uvr+ strains. Excision of thymine-containing dimers does not occur in uvrB mutants, regardless of the rec or sbcA genotype. Survival, after ultraviolet-light damage, of a rec+ sbcA strain is quantitatively similar to rec+ sbcA+ and recB recC sbcA strains.
Similar articles
-
Genetic and physical analysis of plasmid recombination in recB recC sbcB and recB recC sbcA Escherichia coli K-12 mutants.Genetics. 1989 Jun;122(2):269-78. doi: 10.1093/genetics/122.2.269. Genetics. 1989. PMID: 2670665 Free PMC article.
-
Dark-recovery processes in Escherichia coli irradiated with ultraviolet light. 3. Effect of rec mutations on recovery of excision-deficient mutants of Escherichia coli K-12.J Bacteriol. 1970 May;102(2):404-10. doi: 10.1128/jb.102.2.404-410.1970. J Bacteriol. 1970. PMID: 4911540 Free PMC article.
-
Excision repair properties of isogenic rec mutants of Escherichia coli K-12.J Bacteriol. 1972 Sep;111(3):723-30. doi: 10.1128/jb.111.3.723-730.1972. J Bacteriol. 1972. PMID: 4559823 Free PMC article.
-
Repair by genetic recombination in bacteria: overview.Basic Life Sci. 1975;5A:265-74. doi: 10.1007/978-1-4684-2895-7_35. Basic Life Sci. 1975. PMID: 1103833 Review.
-
Repair processes on deoxyribonucleic acid.Angew Chem Int Ed Engl. 1973;12(4):264-73. doi: 10.1002/anie.197302641. Angew Chem Int Ed Engl. 1973. PMID: 4200249 Review. No abstract available.
Cited by
-
Inhibition of bacterial DNA replication by zinc mobilization during nitrosative stress.Proc Natl Acad Sci U S A. 2003 Jul 8;100(14):8496-501. doi: 10.1073/pnas.1033133100. Epub 2003 Jun 26. Proc Natl Acad Sci U S A. 2003. PMID: 12829799 Free PMC article.
References
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources