Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comment
. 2023 Jul 11;56(7):1429-1431.
doi: 10.1016/j.immuni.2023.06.010.

Genetics of autoinflammation instructs selective IL-1 targeting

Cecilia Garlanda  1 , Domenico Supino  2
Affiliations
Free article
Comment

Genetics of autoinflammation instructs selective IL-1 targeting

Cecilia Garlanda et al. Immunity. .
Free article

Abstract

Interleukin-1 (IL-1) is a primary pro-inflammatory cytokine requiring tightly controlled negative regulation. In this issue of Immunity, Wang et al.,1 inspired by an IL-1 receptor missense mutation associated with unleashed IL-1-mediated inflammation, design a new drug to selectively inhibit IL-1.

PubMed Disclaimer

Conflict of interest statement

Declaration of interests The authors declare no competing interests.

Comment on

Publication types

LinkOut - more resources