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Comment
. 2023 Jul 11;35(7):1087-1088.
doi: 10.1016/j.cmet.2023.06.012.

Nonalcoholic fatty liver disease mortality may not be decreasing: A need for careful interpretation of GBD 2019 estimates of liver deaths

James M Paik  1 , Linda Henry  2 , Zobair M Younossi  3
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Free article
Comment

Nonalcoholic fatty liver disease mortality may not be decreasing: A need for careful interpretation of GBD 2019 estimates of liver deaths

James M Paik et al. Cell Metab. .
Free article

Abstract

The Global Burden of Disease (GBD) data provide information on population health; however, careful understanding of the estimation methods and limitations of these data is critical. Herein, Paik et al. discuss the recent study by Chew and colleagues in the context of these limitations, highlighting how a worsening trend in NAFLD-liver mortality may have been underestimated in the analysis.

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Conflict of interest statement

Declaration of interests Z.M.Y. has received research funding and/or serves as consultant to Intercept, Cymabay, Boehringer Ingelheim, BMS, GSK, NovoNordisk, AstraZeneca, Siemens, Madridgal, Merck, and Abbott.

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Comment on

  • The global burden of metabolic disease: Data from 2000 to 2019.
    Chew NWS, Ng CH, Tan DJH, Kong G, Lin C, Chin YH, Lim WH, Huang DQ, Quek J, Fu CE, Xiao J, Syn N, Foo R, Khoo CM, Wang JW, Dimitriadis GK, Young DY, Siddiqui MS, Lam CSP, Wang Y, Figtree GA, Chan MY, Cummings DE, Noureddin M, Wong VW, Ma RCW, Mantzoros CS, Sanyal A, Muthiah MD. Chew NWS, et al. Cell Metab. 2023 Mar 7;35(3):414-428.e3. doi: 10.1016/j.cmet.2023.02.003. Cell Metab. 2023. PMID: 36889281

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