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Comment
. 2023 Aug 1;94(3):189-190.
doi: 10.1016/j.biopsych.2023.04.012.

Alcohol Use Disorder and Posttraumatic Stress Disorder: A Relationship Unbonded by Oxytocin Blockade

Leandro F Vendruscolo  1 , Mary R Lee  2 , Lorenzo Leggio  3
Affiliations
Comment

Alcohol Use Disorder and Posttraumatic Stress Disorder: A Relationship Unbonded by Oxytocin Blockade

Leandro F Vendruscolo et al. Biol Psychiatry. .
No abstract available

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Figures

Figure 1.
Figure 1.
Chronic stress exposure (“trauma”) led to enduring (i.e., during protracted abstinence) sensitization to subsequent stress-induced and stress-related cue-induced relapse to alcohol-seeking behavior, effects that were accompanied by changes in the hypothalamic oxytocin system. Systemic oxytocin administration blocked the sensitized relapse to stress-induced alcohol-seeking behavior.
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