Photoreceptor Ion Channels in Signaling and Disease
- PMID: 37440044
- DOI: 10.1007/978-3-031-27681-1_39
Photoreceptor Ion Channels in Signaling and Disease
Abstract
Photoreceptors (PRs) in the neural retina convert photon capture into an electrical signal that is communicated across a chemical synapse to second-order neurons in the retina and on through the rest of the visual pathway. This information is decoded in the visual cortex to create images. The activity of PRs depends on the concerted action of several voltage-gated ion channels that will be discussed in this chapter.
Keywords: CNG; Cav1.4; HCN1; Ion channels; Kv2.1; Kv8.2; Photoreceptors; Retinal degeneration.
© 2023. The Author(s), under exclusive license to Springer Nature Switzerland AG.
References
-
- Pearring JN, Salinas RY, Baker SA, Arshavsky VY. Protein sorting, targeting and trafficking in photoreceptor cells. Prog Retin Eye Res. 2013;36:24–51. - PubMed
-
- Biel M, Michalakis S. Cyclic nucleotide-gated channels. Handb Exp Pharmacol. 2009;191:111–36.
-
- Craven KB, Zagotta WN. CNG and HCN channels: two peas, one pod. Annu Rev Physiol. 2006;68:375–401. - PubMed
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
