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Editorial
. 2023 May 31;8(7):1287-1289.
doi: 10.1016/j.ekir.2023.05.025. eCollection 2023 Jul.

Identifying the Right Target for New Drugs in Acute Kidney Injury: A Long Way Off?

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Editorial

Identifying the Right Target for New Drugs in Acute Kidney Injury: A Long Way Off?

Kent Doi. Kidney Int Rep. .
No abstract available

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Figures

Figure 1
Figure 1
Concept of biomarker assignment-driven clinical trial in acute kidney injury.

Comment on

  • doi: 10.1016/j.ekir.2023.04.004

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References

    1. Miyamoto Y., Iwagami M., Aso S., et al. Temporal change in characteristics and outcomes of acute kidney injury on renal replacement therapy in intensive care units: analysis of a nationwide administrative database in Japan, 2007–2016. Crit Care. 2019;23:172. doi: 10.1186/s13054-019-2468-8. - DOI - PMC - PubMed
    1. Jo S.K., Rosner M.H., Okusa M.D. Pharmacologic treatment of acute kidney injury: why drugs haven’t worked and what is on the horizon. Clin J Am Soc Nephrol. 2007;2:356–365. doi: 10.2215/CJN.03280906. - DOI - PubMed
    1. Kashani K., Al-Khafaji A., Ardiles T., et al. Discovery and validation of cell cycle arrest biomarkers in human acute kidney injury. Crit Care. 2013;17:R25. doi: 10.1186/cc12503. - DOI - PMC - PubMed
    1. Meersch M., Schmidt C., Hoffmeier A., et al. Prevention of cardiac surgery-associated AKI by implementing the KDIGO guidelines in high risk patients identified by biomarkers: the PrevAKI randomized controlled trial. Intensive Care Med. 2017;43:1551–1561. doi: 10.1007/s00134-016-4670-3. - DOI - PMC - PubMed
    1. Van Till J.W.O., Nojima H., Kameoka C., et al. The effects of peroxisome proliferator-activated receptor delta modulator ASP1128 in patients at risk for acute kidney injury following cardiac surgery. Kidney Int Rep. 2023;8:1407–1416. - PMC - PubMed

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