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Review
. 2023 Jul 3;11(13):1918.
doi: 10.3390/healthcare11131918.

The Effectiveness of the Association of Chlorhexidine with Mechanical Treatment of Peri-Implant Mucositis

Anca Silvia Dumitriu  1 , Stana Păunică  1 , Ximena Anca Nicolae  2 , Dana Cristina Bodnar  3 , Ștefan Dimitrie Albu  1 , Ioana Suciu  4 , Dragoș Nicolae Ciongaru  1 , Marina Cristina Giurgiu  1
Affiliations
Review

The Effectiveness of the Association of Chlorhexidine with Mechanical Treatment of Peri-Implant Mucositis

Anca Silvia Dumitriu et al. Healthcare (Basel). .

Abstract

(1) Background: The aim of the study was to evaluate the benefit of combining chlorhexidine with the mechanical treatment of peri-implant mucositis. (2) Methods: Articles from 2016 to 2021 included in the PubMed and Scopus databases were analyzed, following the PICOS criteria and the randomized controlled study model that used chlorhexidine in various forms in the treatment of peri-mucositis. According to the established criteria, a limited number of studies were selected. These studies had as their criteria of evaluation for the effectiveness of chlorhexidine, plaque indices, bleeding indices and depth probing indices. Chlorhexidine has been used after mechanical debridement as a solution, with different concentrations of 0.06%/0.12%/0.2% alone or in a concentration of 0.03%, in combination with 0.05% cetylpyridinium chloride, as well as in the form of a gel with a concentration of 0.2%. (3) Results: The results were assessed to a placebo or other substances, and showed a significant reduction in the indices with a follow-up period ranging from 3 months to 1 year. (4) Conclusions: The association of chlorhexidine with the mechanical treatment of peri-implant mucositis has a role in reducing inflammation, although a complete remission was not obtained in all cases, and the results were not statistically significantly different from the use of other antiseptics.

Keywords: chlorhexidine; non-surgical treatment; oral hygiene; peri-implant mucositis.

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
The evaluation criteria for the effectiveness of CHX in mucositis treatment.
See this image and copyright information in PMC

References

    1. Heitz-Mayfield L.J.A., Salvi G.E. Peri-implant mucositis. J. Clin. Periodontol. 2018;45((Suppl. 20)):S237–S245. doi: 10.1111/jcpe.12953. - DOI - PubMed
    1. Derks J., Tomasi C. Peri-implant health and disease. A systematic review of current epidemiology. J. Clin. Periodontol. 2015;42((Suppl. S16)):S158–S171. doi: 10.1111/jcpe.12334. - DOI - PubMed
    1. Peña M., Barallat L., Vilarrasa J., Vicario M., Violant D., Nart J. Evaluation of the effect of probiotics in the treatment of peri-implant mucositis: A triple-blind randomized clinical trial. Clin. Oral Investig. 2019;23:1673–1683. doi: 10.1007/s00784-018-2578-8. - DOI - PubMed
    1. Renvert S., Persson G.R., Pirih F.Q., Camargo P.M. Peri-implant health, peri-implant mucositis, and peri-implantitis: Case definitions and diagnostic considerations. J. Clin. Periodontol. 2018;45:S278–S285. doi: 10.1111/jcpe.12956. - DOI - PubMed
    1. Papathanasiou E., Finkelman M., Hanley J., Parashis A. Prevalence, Etiology and Treatment of Peri-Implant Mucositis and Peri-Implantitis: A Survey of Periodontists in the United States. J. Periodontol. 2016;87:493–501. doi: 10.1902/jop.2015.150476. - DOI - PubMed

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