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Review
. 2023 Jul 7;12(13):4537.
doi: 10.3390/jcm12134537.

Advances in PET/CT Imaging for Breast Cancer

Dorine de Jong  1 , Elise Desperito  2 , Karine A Al Feghali  3 , Laurent Dercle  2 , Romain-David Seban  4   5 , Jeeban P Das  6 , Hong Ma  2 , Abin Sajan  2 , Brian Braumuller  2 , Conor Prendergast  2 , Connie Liou  2 , Aileen Deng  7 , Tina Roa  2 , Randy Yeh  6 , Antoine Girard  8 , Mary M Salvatore  2 , Kathleen M Capaccione  2
Affiliations
Review

Advances in PET/CT Imaging for Breast Cancer

Dorine de Jong et al. J Clin Med. .

Abstract

One out of eight women will be affected by breast cancer during her lifetime. Imaging plays a key role in breast cancer detection and management, providing physicians with information about tumor location, heterogeneity, and dissemination. In this review, we describe the latest advances in PET/CT imaging of breast cancer, including novel applications of 18F-FDG PET/CT and the development and testing of new agents for primary and metastatic breast tumor imaging and therapy. Ultimately, these radiopharmaceuticals may guide personalized approaches to optimize treatment based on the patient's specific tumor profile, and may become a new standard of care. In addition, they may enhance the assessment of treatment efficacy and lead to improved outcomes for patients with a breast cancer diagnosis.

Keywords: 18F-FDG; PET radiotracers; breast cancer; triple negative breast cancer (TNBC).

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Conflict of interest statement

Capaccione has served as an advisor for Cardinal Health. Salvatore is a speaker and consultant for Genentech and Boehringer Ingelheim, and has received grant funding from Genentech and Boehringer Ingelheim. The remaining authors have nothing to disclose. No funding was obtained for this study.

Figures

Figure 1
Figure 1
Strategies to improve PET/CT imaging of breast cancer patients.
See this image and copyright information in PMC

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