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. 1986 Sep;53(3):713-4.
doi: 10.1128/iai.53.3.713-714.1986.

Passive immunization of hamsters against experimental infection with the Lyme disease spirochete

R C Johnson, C Kodner, M Russell

Passive immunization of hamsters against experimental infection with the Lyme disease spirochete

R C Johnson et al. Infect Immun. 1986 Sep.

Abstract

Hamsters passively immunized with as little as 0.0125 ml of immune rabbit serum (indirect fluorescent-antibody titer, 1:8,192) were protected from challenge with 1,000 50% infective doses of Borrelia burgdorferi. Cross-protection studies with Minnesota and Connecticut isolates of B. burgdorferi indicated no major differences in their capacity to elicit mutually protective antibodies in rabbits.

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