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. 2023 Jun 23;15(13):2849.
doi: 10.3390/nu15132849.

Malnutrition, Depression, Poor Sleep Quality, and Difficulty Falling Asleep at Night Are Associated with a Higher Risk of Cognitive Frailty in Older Adults during the COVID-19 Restrictions

Jiranan Griffiths  1 , Mathuramat Seesen  2 , Wachiranun Sirikul  2   3 , Penprapa Siviroj  2
Affiliations

Malnutrition, Depression, Poor Sleep Quality, and Difficulty Falling Asleep at Night Are Associated with a Higher Risk of Cognitive Frailty in Older Adults during the COVID-19 Restrictions

Jiranan Griffiths et al. Nutrients. .

Abstract

The COVID-19 restrictions, such as social isolation and disruption of daily routines, can have detrimental effects, including increased stress, anxiety, sleep disturbance, and physical and cognitive decline among older adults. This study aimed to examine the association between nutritional status, depression, sleep quality, falling asleep at night, and cognitive frailty (CF) among older Thai adults during the COVID-19 pandemic. This cross-sectional study included 408 older adults with an average age of 70.54 (5.49) years. CF was determined using Fried's frailty phenotype and the Montreal Cognitive Assessment Basic. The Mini Nutritional Assessment-Short Form, Pittsburgh Sleep Quality Index, and geriatric depression assessment were used for assessment. Multiple logistic regression analysis demonstrated that participants who were malnourished (OR 3.786; 95%CI 1.719-8.335), depressed (OR 5.003; 95%CI 2.399-10.434), had poor sleep quality (OR 1.613; 95%CI 1.041-2.500), and engaged in difficulty falling asleep (OR 1.809; 95%CI 1.022-3.203) had a higher risk of CF compared to those who did not exhibit these factors. Therefore, malnutrition, depression, poor sleep quality, and difficulty falling asleep were identified as risk factors for CF among older adults in Thailand linked to the impact of the COVID-19 pandemic. It is crucial to develop interventions to prevent CF resulting from the mentioned variables.

Keywords: COVID-19 restrictions; cognitive frailty; depression; falling asleep at night; malnutrition; older adults; sleep quality.

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
Diagram of the study participant selection. Abbreviations: MoCA-B, Montreal Cognitive Assessment-Basic; TGDS-15, Thai version of 15-item Geriatric Depression Scale; PSQI, Pittsburgh Sleep Quality Index.
Figure 2
Figure 2
The histogram illustrates the proportion for (a) physical frailty and its characteristics and (b) mild cognitive impairment and all components in cognitively frail and non-cognitively frail groups. The differences between two groups were analyzed by Fisher’s Exact test.
See this image and copyright information in PMC

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