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Review
. 2023 Jun 20;4(4):100461.
doi: 10.1016/j.xinn.2023.100461. eCollection 2023 Jul 10.

Treatment options for adult intermediate-risk AML patients in CR1: Allo-HSCT or chemotherapy?

Affiliations
Review

Treatment options for adult intermediate-risk AML patients in CR1: Allo-HSCT or chemotherapy?

Luxiang Wang et al. Innovation (Camb). .
No abstract available

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Conflict of interest statement

The authors declare no competing interests.

Figures

Figure 1
Figure 1
The proposed paradigm of the MRD-directed randomized trial in adult intermediate-risk AML patients

References

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    1. Dillon L.W., Gui G., Page K.M., et al. DNA sequencing to detect residual disease in adults with acute myeloid leukemia prior to hematopoietic cell transplant. JAMA. 2023;329:745–755. - PMC - PubMed
    1. Venditti A., Piciocchi A., Candoni A., et al. GIMEMA AML1310 trial of risk-adapted, MRD-directed therapy for young adults with newly diagnosed acute myeloid leukemia. Blood. 2019;134:935–945. - PubMed
    1. Jentzsch M., Bischof L., Backhaus D., et al. Impact of MRD status in patients with AML undergoing allogeneic stem cell transplantation in the first vs the second remission. Blood Adv. 2022;6:4570–4580. - PMC - PubMed
    1. Lv M., Wang Y., Chang Y.J., et al. Myeloablative haploidentical transplantation is superior to chemotherapy for patients with intermediate-risk acute myelogenous leukemia in first complete remission. Clin. Cancer Res. 2019;25:1737–1748. - PubMed

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