Vaccine-Boosted CAR T-cell Therapy Elicits Antigen Spreading
- PMID: 37449732
- DOI: 10.1158/2159-8290.CD-RW2023-112
Vaccine-Boosted CAR T-cell Therapy Elicits Antigen Spreading
Abstract
Vaccine-boosted CAR T cells induce antigen spreading to control antigenically heterogeneous tumors.
©2023 American Association for Cancer Research.
Comment on
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Vaccine-boosted CAR T crosstalk with host immunity to reject tumors with antigen heterogeneity.Cell. 2023 Jul 20;186(15):3148-3165.e20. doi: 10.1016/j.cell.2023.06.002. Epub 2023 Jul 5. Cell. 2023. PMID: 37413990 Free PMC article.
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