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Case Reports
. 2023 Jul 1;91(1):62-63.
doi: 10.1097/SAP.0000000000003589.

Pemphigus Vulgaris: More Than Just a Skin Disease

Samuel Ruiz  1 , Brittany Puebla  2 , Noel Hernandez  2 , Viviana Rubio  2 , Elizabeth Young  2 , Haaris Mir  2
Affiliations
Case Reports

Pemphigus Vulgaris: More Than Just a Skin Disease

Samuel Ruiz et al. Ann Plast Surg. .

Abstract

Introduction: Pemphigus is a group of autoimmune diseases of the skin and mucous membranes that is characterized by multiple bullae formation. It is caused by autoantibodies directed against the cell surface of keratinocytes, resulting in the loss of cell-cell adhesion of keratinocytes. This disease can be very debilitating and difficult to treat if large surface areas are involved.

Methods: We performed a retrospective review of a complex case of pemphigus vulgaris in a 24-year-old man who develop partial-thickness skin lesions distributed throughout the entire body with a total body surface of 80% short after an episode of strep throat treated with amoxicillin.

Results: The patient had a complicated hospital course in which the standard treatment of the disease led to adverse effects that were successfully managed at our busy burn center.

Conclusions: Pemphigus vulgaris is a complex skin disease in which treatment techniques carry their risk and must be tailored to the patient's specific needs. Treatment of this conditions at a burn center would be beneficial as demonstrated with conditions like Stevens-Johnson syndrome and toxic epidermal necrolysis.

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Conflict of interest statement

Conflicts of interest and sources of funding: none declared.

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