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. 2023 Sep 1;208(5):524-527.
doi: 10.1164/rccm.202212-2234VP.

Revised Paradigm for Acute Pulmonary Embolism Prognostication and Treatment

Affiliations

Revised Paradigm for Acute Pulmonary Embolism Prognostication and Treatment

David Jiménez et al. Am J Respir Crit Care Med. .
No abstract available

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Figures

Figure 1.
Figure 1.
(A) Proposed approach for generating the therapy-stratified risk classification for guiding acute pulmonary embolism (PE) management schema. (B) Limited prognosis-guided risk classification versus proposed therapy-stratified risk classification for guiding acute PE management schemas. CDT = catheter-directed therapies; ESC = European Society of Cardiology; RV = right ventricle; SBP = systolic blood pressure; sPESI = simplified Pulmonary Embolism Severity Index. Thresholds for the therapeutic-guided risk classification used to illustrate the concept, but not proposed for implementation.

References

    1. Jiménez D, de Miguel-Díez J, Guijarro R, Trujillo-Santos J, Otero R, Barba R, et al. RIETE Investigators Trends in the management and outcomes of acute pulmonary embolism: analysis from the RIETE registry. J Am Coll Cardiol . 2016;67:162–170. - PubMed
    1. Bova C, Sanchez O, Prandoni P, Lankeit M, Konstantinides S, Vanni S, et al. Identification of intermediate-risk patients with acute symptomatic pulmonary embolism: analysis of individual participants’ data from six studies. Eur Respir J . 2014;44:694–703. - PubMed
    1. Kearon C, Akl EA, Comerota AJ, Prandoni P, Bounameaux H, Goldhaber SZ, et al. Antithrombotic therapy for VTE disease: antithrombotic therapy and prevention of thrombosis, 9th ed: American College of Chest Physicians Evidence-based Clinical Practice Guidelines. Chest . 2012;141(2 Suppl):e419S–e494S. - PMC - PubMed
    1. Jiménez D, Kopecna D, Tapson V, Briese B, Schreiber D, Lobo JL, et al. Protect Investigators Derivation and validation of multimarker prognostication for normotensive patients with acute symptomatic pulmonary embolism. Am J Respir Crit Care Med . 2014;189:718–726. - PubMed
    1. Jiménez D, Rodríguez C, León F, Jara-Palomares L, López-Reyes R, Ruiz-Artacho P, et al. IPEP investigators Randomised controlled trial of a prognostic assessment and management pathway to reduce the length of hospital stay in normotensive patients with acute pulmonary embolism. Eur Respir J . 2022;59:2100412. - PubMed