Low-density lipoprotein cholesterol cannot be too low after a myocardial infarction

Anders B Wulff^{1

2

3}, Martin B Mortensen^{2

4

5}, Børge G Nordestgaard^{1

2

3

6}

Affiliations

¹ Department of Clinical Biochemistry, Herlev and Gentofte Hospital, Copenhagen University Hospital, Herlev, Denmark.
² The Copenhagen General Population Study, Herlev and Gentofte Hospital, Copenhagen University Hospital, Herlev, Denmark.
³ Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
⁴ Department of Cardiology, Aarhus University Hospital, Aarhus, Denmark.
⁵ Johns Hopkins Ciccarone Center for the Prevention of Cardiovascular Disease, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
⁶ The Copenhagen City Heart Study, Frederiksberg Hospital, Copenhagen University Hospital, Frederiksberg, Denmark.

Editorial

Anders B Wulff et al. J Intern Med. 2023 Nov.

. 2023 Nov;294(5):540-542.

doi: 10.1111/joim.13694. Epub 2023 Jul 16.

Anders B Wulff^{1

2

3}, Martin B Mortensen^{2

4

5}, Børge G Nordestgaard^{1

2

3

6}

¹ Department of Clinical Biochemistry, Herlev and Gentofte Hospital, Copenhagen University Hospital, Herlev, Denmark.
² The Copenhagen General Population Study, Herlev and Gentofte Hospital, Copenhagen University Hospital, Herlev, Denmark.
³ Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
⁴ Department of Cardiology, Aarhus University Hospital, Aarhus, Denmark.
⁵ Johns Hopkins Ciccarone Center for the Prevention of Cardiovascular Disease, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
⁶ The Copenhagen City Heart Study, Frederiksberg Hospital, Copenhagen University Hospital, Frederiksberg, Denmark.

No abstract available

References

1. Ference BA, Ginsberg HN, Graham I, Ray KK, Packard CJ, Bruckert E, et al. Low-density lipoproteins cause atherosclerotic cardiovascular disease. 1. Evidence from genetic, epidemiologic, and clinical studies. A consensus statement from the European Atherosclerosis Society Consensus Panel. Eur Heart J. 2017;38:2459-72.
1. Boren J, Chapman MJ, Krauss RM, Raal FJ, Schunkert H, Watts GF, et al. Low-density lipoproteins cause atherosclerotic cardiovascular disease: pathophysiological, genetic, and therapeutic insights: a consensus statement from the European Atherosclerosis Society Consensus Panel. Eur Heart J. 2020;41:2313-30.
1. Nissen SE, Lincoff AM, Brennan D, Ray KK, Mason D, Kastelein JJP, et al. Bempedoic acid and cardiovascular outcomes in statin-intolerant patients. N Engl J Med. 2023;388:1353-64.
1. Schubert J, Lindahl B, Melhus H, Renlund H, Leosdottir M, Yari A, et al. Elevated low-density lipoprotein cholesterol: an inverse marker of morbidity and mortality in patients with myocardial infarction. J Intern Med. 2023;294(5):616-27.
1. Banack HR, Stokes A. The ‘obesity paradox’ may not be a paradox at all. Int J Obes (Lond). 2017;41:1162-3.